Effect of optical technical of guiding emmetropization lenses on myopia prevention in children without myopia

Abstract Accelerated emmetropization may result in premature onset of myopia. And there is a lack of reports on the effect of peripheral defocus spectacle lenses in non-myopia children. The purpose of this study was to investigate the significance of preventing myopia using Optical Technical Of Guid...

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Main Authors: Qi Zhao, Jiaqi Li, Tiangang Liang, Jie Cheng, Weixiang Nie, Yanhua Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-98526-7
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author Qi Zhao
Jiaqi Li
Tiangang Liang
Jie Cheng
Weixiang Nie
Yanhua Wang
author_facet Qi Zhao
Jiaqi Li
Tiangang Liang
Jie Cheng
Weixiang Nie
Yanhua Wang
author_sort Qi Zhao
collection DOAJ
description Abstract Accelerated emmetropization may result in premature onset of myopia. And there is a lack of reports on the effect of peripheral defocus spectacle lenses in non-myopia children. The purpose of this study was to investigate the significance of preventing myopia using Optical Technical Of Guiding Emmetropization (O.T.O.G.E.) lenses in non-myopic children aged 5–8 years. This non-randomized controlled study enrolled 110 non-myopic children aged 5–8 years. Participants were assigned to two groups. One group (experimental group, 55 eyes) wore O.T.O.G.E. lenses, while the other group (control group, 55 eyes) wore no spectacles. Refractive outcomes and axial length (AL) were measured in all subjects and then again six months and one year later for comparison. T-tests were used to compare the growth of spherical equivalent refraction (SE) and AL between the two groups. At the end of six months, the experimental group had less SE myopic shift and AL elongation than the control group (0.01 ± 0.20D vs. 0.32 ± 0.38D, 0.08 ± 0.06 mm vs. 0.19 ± 0.09 mm, respectively) (P < 0.01). Moreover, at the end of one year, the experimental group had less SE myopic shift and AL elongation than the control group (0.26 ± 0.26D vs. 0.55 ± 0.59D, 0.21 ± 0.09 mm vs. 0.44 ± 0.20 mm, respectively) (P < 0.01). Wearing O.T.O.G.E. lenses in non-myopic children aged 5–8 years attenuated hyperopic reduction, slowed AL elongation, and delayed myopia onset.
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spelling doaj-art-a983a626d92c4bf39e47b96bc4ceee072025-08-20T03:14:10ZengNature PortfolioScientific Reports2045-23222025-04-011511610.1038/s41598-025-98526-7Effect of optical technical of guiding emmetropization lenses on myopia prevention in children without myopiaQi Zhao0Jiaqi Li1Tiangang Liang2Jie Cheng3Weixiang Nie4Yanhua Wang5Shanxi Aier Eye Hospital, Aier Eye Hospital GroupShanxi Aier Eye Hospital, Aier Eye Hospital GroupShanxi Aier Eye Hospital, Aier Eye Hospital GroupShanxi Aier Eye Hospital, Aier Eye Hospital GroupShanxi Aier Eye Hospital, Aier Eye Hospital GroupShanxi Aier Eye Hospital, Aier Eye Hospital GroupAbstract Accelerated emmetropization may result in premature onset of myopia. And there is a lack of reports on the effect of peripheral defocus spectacle lenses in non-myopia children. The purpose of this study was to investigate the significance of preventing myopia using Optical Technical Of Guiding Emmetropization (O.T.O.G.E.) lenses in non-myopic children aged 5–8 years. This non-randomized controlled study enrolled 110 non-myopic children aged 5–8 years. Participants were assigned to two groups. One group (experimental group, 55 eyes) wore O.T.O.G.E. lenses, while the other group (control group, 55 eyes) wore no spectacles. Refractive outcomes and axial length (AL) were measured in all subjects and then again six months and one year later for comparison. T-tests were used to compare the growth of spherical equivalent refraction (SE) and AL between the two groups. At the end of six months, the experimental group had less SE myopic shift and AL elongation than the control group (0.01 ± 0.20D vs. 0.32 ± 0.38D, 0.08 ± 0.06 mm vs. 0.19 ± 0.09 mm, respectively) (P < 0.01). Moreover, at the end of one year, the experimental group had less SE myopic shift and AL elongation than the control group (0.26 ± 0.26D vs. 0.55 ± 0.59D, 0.21 ± 0.09 mm vs. 0.44 ± 0.20 mm, respectively) (P < 0.01). Wearing O.T.O.G.E. lenses in non-myopic children aged 5–8 years attenuated hyperopic reduction, slowed AL elongation, and delayed myopia onset.https://doi.org/10.1038/s41598-025-98526-7MyopiaOptical technical of guiding emmetropizationSpherical equivalent refractionAxial lengthProgression of the emmetropization
spellingShingle Qi Zhao
Jiaqi Li
Tiangang Liang
Jie Cheng
Weixiang Nie
Yanhua Wang
Effect of optical technical of guiding emmetropization lenses on myopia prevention in children without myopia
Scientific Reports
Myopia
Optical technical of guiding emmetropization
Spherical equivalent refraction
Axial length
Progression of the emmetropization
title Effect of optical technical of guiding emmetropization lenses on myopia prevention in children without myopia
title_full Effect of optical technical of guiding emmetropization lenses on myopia prevention in children without myopia
title_fullStr Effect of optical technical of guiding emmetropization lenses on myopia prevention in children without myopia
title_full_unstemmed Effect of optical technical of guiding emmetropization lenses on myopia prevention in children without myopia
title_short Effect of optical technical of guiding emmetropization lenses on myopia prevention in children without myopia
title_sort effect of optical technical of guiding emmetropization lenses on myopia prevention in children without myopia
topic Myopia
Optical technical of guiding emmetropization
Spherical equivalent refraction
Axial length
Progression of the emmetropization
url https://doi.org/10.1038/s41598-025-98526-7
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