Occurrence of the alcoholic tolerance phenomenon and their relationships with daily frequency of ethanol doses and with the presence of an withdrawal interval, in an experimental model of alcoholism in rats

In this paper we present the effects of the number of daily toxic doses of alcohol and of the duration of withdrawal period on alcohol tolerance in rats submitted to cycles of 21 doses each. It was observed that alcohol tolerance was increased in animals which received less number of alcohol doses b...

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Main Authors: J. O. Cardeal, E. A. Cavalheiro
Format: Article
Language:English
Published: Thieme Revinter Publicações 1987-03-01
Series:Arquivos de Neuro-Psiquiatria
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1987000100001&lng=en&tlng=en
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author J. O. Cardeal
E. A. Cavalheiro
author_facet J. O. Cardeal
E. A. Cavalheiro
author_sort J. O. Cardeal
collection DOAJ
description In this paper we present the effects of the number of daily toxic doses of alcohol and of the duration of withdrawal period on alcohol tolerance in rats submitted to cycles of 21 doses each. It was observed that alcohol tolerance was increased in animals which received less number of alcohol doses by day and that some degree of tolerance can be detected even after a withdrawal interval of 15 days.
format Article
id doaj-art-a983511e638141b3a8fce8fea852cd3f
institution OA Journals
issn 1678-4227
language English
publishDate 1987-03-01
publisher Thieme Revinter Publicações
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series Arquivos de Neuro-Psiquiatria
spelling doaj-art-a983511e638141b3a8fce8fea852cd3f2025-08-20T02:23:06ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42271987-03-014511610.1590/S0004-282X1987000100001S0004-282X1987000100001Occurrence of the alcoholic tolerance phenomenon and their relationships with daily frequency of ethanol doses and with the presence of an withdrawal interval, in an experimental model of alcoholism in ratsJ. O. Cardeal0E. A. Cavalheiro1Universidade Federal de São PauloUniversidade Federal de São PauloIn this paper we present the effects of the number of daily toxic doses of alcohol and of the duration of withdrawal period on alcohol tolerance in rats submitted to cycles of 21 doses each. It was observed that alcohol tolerance was increased in animals which received less number of alcohol doses by day and that some degree of tolerance can be detected even after a withdrawal interval of 15 days.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1987000100001&lng=en&tlng=en
spellingShingle J. O. Cardeal
E. A. Cavalheiro
Occurrence of the alcoholic tolerance phenomenon and their relationships with daily frequency of ethanol doses and with the presence of an withdrawal interval, in an experimental model of alcoholism in rats
Arquivos de Neuro-Psiquiatria
title Occurrence of the alcoholic tolerance phenomenon and their relationships with daily frequency of ethanol doses and with the presence of an withdrawal interval, in an experimental model of alcoholism in rats
title_full Occurrence of the alcoholic tolerance phenomenon and their relationships with daily frequency of ethanol doses and with the presence of an withdrawal interval, in an experimental model of alcoholism in rats
title_fullStr Occurrence of the alcoholic tolerance phenomenon and their relationships with daily frequency of ethanol doses and with the presence of an withdrawal interval, in an experimental model of alcoholism in rats
title_full_unstemmed Occurrence of the alcoholic tolerance phenomenon and their relationships with daily frequency of ethanol doses and with the presence of an withdrawal interval, in an experimental model of alcoholism in rats
title_short Occurrence of the alcoholic tolerance phenomenon and their relationships with daily frequency of ethanol doses and with the presence of an withdrawal interval, in an experimental model of alcoholism in rats
title_sort occurrence of the alcoholic tolerance phenomenon and their relationships with daily frequency of ethanol doses and with the presence of an withdrawal interval in an experimental model of alcoholism in rats
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1987000100001&lng=en&tlng=en
work_keys_str_mv AT jocardeal occurrenceofthealcoholictolerancephenomenonandtheirrelationshipswithdailyfrequencyofethanoldosesandwiththepresenceofanwithdrawalintervalinanexperimentalmodelofalcoholisminrats
AT eacavalheiro occurrenceofthealcoholictolerancephenomenonandtheirrelationshipswithdailyfrequencyofethanoldosesandwiththepresenceofanwithdrawalintervalinanexperimentalmodelofalcoholisminrats