Treatment outcomes of burn injury and its associated factor among children in Sub-Saharan Africa: a systematic review and meta-analysis
Abstract Background Burns are a prominent cause of unintentional injury, mortality, and disability. In addition to being a personal disaster for the victim, severe burns are a medical concern and financial burden on national health systems. This systematic review and meta-analysis aimed to provide s...
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| Format: | Article |
| Language: | English |
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BMC
2025-07-01
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| Series: | BMC Pediatrics |
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| Online Access: | https://doi.org/10.1186/s12887-025-05859-3 |
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| author | Endalk Birrie Wondifraw Fekadeselassie Belege Getaneh Muluken Amare Gebeyaw Biset Birhanu Desu Tefera Mulusew Zeleke Melkamu Senbeta Jimma Ermias Sisay Chanie |
| author_facet | Endalk Birrie Wondifraw Fekadeselassie Belege Getaneh Muluken Amare Gebeyaw Biset Birhanu Desu Tefera Mulusew Zeleke Melkamu Senbeta Jimma Ermias Sisay Chanie |
| author_sort | Endalk Birrie Wondifraw |
| collection | DOAJ |
| description | Abstract Background Burns are a prominent cause of unintentional injury, mortality, and disability. In addition to being a personal disaster for the victim, severe burns are a medical concern and financial burden on national health systems. This systematic review and meta-analysis aimed to provide solid evidence on the prevalence of poor treatment outcomes and the associated factors of poor treatment outcomes of burn injuries among children in sub-Saharan Africa. Methods We searched several databases, including PubMed, Medline, Central, Hinary, Cochrane Library, African Journals Online, Web of Science, and Google on December 26, 2023. The quality of the papers was assessed using the Joanna Briggs Institute (JBI) critical appraisal checklist for observational studies. Inclusion criteria were observational studies, case–control, cross-sectional, and cohort studies in English, published or unpublished, full-text, from January 30, 2000, to December 26, 2023. Data were extracted using Microsoft Excel and analyzed with STATA V.17 Statistical Software. Publication bias was assessed graphically with a funnel plot and statistically with Egger’s regression and Begg’s tests. Result This systematic review and meta-analysis includes 18 studies. The overall prevalence of poor treatment outcomes for burn injuries was 15.99% (95% CI 11.32% to 20.66%). The study found that characteristics such as age under five years (POR = 8.57 (95% CI: 3.35 to 13.78)), TBSA (total body surface area) greater than 20% (POR = 10.59 (95% CI: 2.87–18.31)), flame burn (POR = 3.87, 95% CI (1.19–6.56)), and malnutrition (POR = 3.26, 95% CI (1.91–4.61)) were related to poor treatment outcomes. Conclusion The prevalence of poor treatment outcomes for burn injuries among children in Sub-Saharan Africa was high. The poor treatment outcomes of burn injuries are associated with age, TBSA, burn type, and malnutrition. Addressing these factors through targeted interventions, developing nutritional support programs for children, improved healthcare infrastructure and supportive policies can significantly enhance treatment outcomes. |
| format | Article |
| id | doaj-art-a9785823fa4c414e867f8f56ee172b97 |
| institution | Kabale University |
| issn | 1471-2431 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pediatrics |
| spelling | doaj-art-a9785823fa4c414e867f8f56ee172b972025-08-20T03:45:32ZengBMCBMC Pediatrics1471-24312025-07-0125111210.1186/s12887-025-05859-3Treatment outcomes of burn injury and its associated factor among children in Sub-Saharan Africa: a systematic review and meta-analysisEndalk Birrie Wondifraw0Fekadeselassie Belege Getaneh1Muluken Amare2Gebeyaw Biset3Birhanu Desu Tefera4Mulusew Zeleke5Melkamu Senbeta Jimma6Ermias Sisay Chanie7Department of Pediatric and Child Health Nursing, College of Medicine and Health Science, Wollo UniversityDepartment of Pediatric and Child Health Nursing, College of Medicine and Health Science, Wollo UniversityDepartment of Pediatric and Child Health Nursing, College of Medicine and Health Science, Wollo UniversityDepartment of Pediatric and Child Health Nursing, College of Medicine and Health Science, Wollo UniversityDepartment of Emergency and Critical Care Nursing, College of Medicine and Health Science, Wollo UniversityDepartment of Surgical Nursing, College of Medicine and Health Science, Wollo UniversityDepartment of Nursing, Faculty of Health Science, Assosa UniversityDepartment of Pediatrics and Child Health Nursing, College of Health Science, Debre Tabor UniversityAbstract Background Burns are a prominent cause of unintentional injury, mortality, and disability. In addition to being a personal disaster for the victim, severe burns are a medical concern and financial burden on national health systems. This systematic review and meta-analysis aimed to provide solid evidence on the prevalence of poor treatment outcomes and the associated factors of poor treatment outcomes of burn injuries among children in sub-Saharan Africa. Methods We searched several databases, including PubMed, Medline, Central, Hinary, Cochrane Library, African Journals Online, Web of Science, and Google on December 26, 2023. The quality of the papers was assessed using the Joanna Briggs Institute (JBI) critical appraisal checklist for observational studies. Inclusion criteria were observational studies, case–control, cross-sectional, and cohort studies in English, published or unpublished, full-text, from January 30, 2000, to December 26, 2023. Data were extracted using Microsoft Excel and analyzed with STATA V.17 Statistical Software. Publication bias was assessed graphically with a funnel plot and statistically with Egger’s regression and Begg’s tests. Result This systematic review and meta-analysis includes 18 studies. The overall prevalence of poor treatment outcomes for burn injuries was 15.99% (95% CI 11.32% to 20.66%). The study found that characteristics such as age under five years (POR = 8.57 (95% CI: 3.35 to 13.78)), TBSA (total body surface area) greater than 20% (POR = 10.59 (95% CI: 2.87–18.31)), flame burn (POR = 3.87, 95% CI (1.19–6.56)), and malnutrition (POR = 3.26, 95% CI (1.91–4.61)) were related to poor treatment outcomes. Conclusion The prevalence of poor treatment outcomes for burn injuries among children in Sub-Saharan Africa was high. The poor treatment outcomes of burn injuries are associated with age, TBSA, burn type, and malnutrition. Addressing these factors through targeted interventions, developing nutritional support programs for children, improved healthcare infrastructure and supportive policies can significantly enhance treatment outcomes.https://doi.org/10.1186/s12887-025-05859-3BurnTreatmentOutcomesChildrenSub-Saharan Africa |
| spellingShingle | Endalk Birrie Wondifraw Fekadeselassie Belege Getaneh Muluken Amare Gebeyaw Biset Birhanu Desu Tefera Mulusew Zeleke Melkamu Senbeta Jimma Ermias Sisay Chanie Treatment outcomes of burn injury and its associated factor among children in Sub-Saharan Africa: a systematic review and meta-analysis BMC Pediatrics Burn Treatment Outcomes Children Sub-Saharan Africa |
| title | Treatment outcomes of burn injury and its associated factor among children in Sub-Saharan Africa: a systematic review and meta-analysis |
| title_full | Treatment outcomes of burn injury and its associated factor among children in Sub-Saharan Africa: a systematic review and meta-analysis |
| title_fullStr | Treatment outcomes of burn injury and its associated factor among children in Sub-Saharan Africa: a systematic review and meta-analysis |
| title_full_unstemmed | Treatment outcomes of burn injury and its associated factor among children in Sub-Saharan Africa: a systematic review and meta-analysis |
| title_short | Treatment outcomes of burn injury and its associated factor among children in Sub-Saharan Africa: a systematic review and meta-analysis |
| title_sort | treatment outcomes of burn injury and its associated factor among children in sub saharan africa a systematic review and meta analysis |
| topic | Burn Treatment Outcomes Children Sub-Saharan Africa |
| url | https://doi.org/10.1186/s12887-025-05859-3 |
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