Squamous Cell Carcinoma in Combination with a Symbrachydactyly: Initial Management and Long-Term Followup
A 68-year-old female patient presented with a rapidly growing, exulcerating tumor of the left hand in the area of a congenital symbrachydactyly at the digiti II and III. A biopsy of the tumor showed a squamous cell carcinoma. Further workup showed two suspicious axillar enhancements with no evidence...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Orthopedics |
| Online Access: | http://dx.doi.org/10.1155/2014/684130 |
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| author | Tomas Sanchez Daniel Walder Philipp Esenwein |
| author_facet | Tomas Sanchez Daniel Walder Philipp Esenwein |
| author_sort | Tomas Sanchez |
| collection | DOAJ |
| description | A 68-year-old female patient presented with a rapidly growing, exulcerating tumor of the left hand in the area of a congenital symbrachydactyly at the digiti II and III. A biopsy of the tumor showed a squamous cell carcinoma. Further workup showed two suspicious axillar enhancements with no evidence of bony infiltration and no further metastasis. An amputation of the second and third ray of the left hand at the metacarpal level and additionally an axillar revision and lymph node dissection were performed and confirmed the suspicion of a squamous cell carcinoma, fortunately without affection of any lymph nodes. After 9 years the patient showed an excellent function of the left hand. Symbrachydactyly malformations and squamous cell carcinoma of the hand are both rare conditions. We could not find a reference that shows a common genetic condition to both and so far this is the first description of a squamous cell carcinoma in the region of a symbrachydactyly. It remains unclear whether our case is a coincidence of two rare independent diseases or there is a pathogenetic link between the malformation and the tumor on a genetic level. |
| format | Article |
| id | doaj-art-a96ce69f29f84ffd910a8b806a29541b |
| institution | OA Journals |
| issn | 2090-6749 2090-6757 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Orthopedics |
| spelling | doaj-art-a96ce69f29f84ffd910a8b806a29541b2025-08-20T02:23:07ZengWileyCase Reports in Orthopedics2090-67492090-67572014-01-01201410.1155/2014/684130684130Squamous Cell Carcinoma in Combination with a Symbrachydactyly: Initial Management and Long-Term FollowupTomas Sanchez0Daniel Walder1Philipp Esenwein2Department of Orthopaedic Surgery, Kantonsspital Olten, Baslerstraße 150, 4600 Olten, SwitzerlandDepartment of Orthopaedic Surgery, Kantonsspital Olten, Baslerstraße 150, 4600 Olten, SwitzerlandDepartment of Orthopaedic Surgery, Kantonsspital Olten, Baslerstraße 150, 4600 Olten, SwitzerlandA 68-year-old female patient presented with a rapidly growing, exulcerating tumor of the left hand in the area of a congenital symbrachydactyly at the digiti II and III. A biopsy of the tumor showed a squamous cell carcinoma. Further workup showed two suspicious axillar enhancements with no evidence of bony infiltration and no further metastasis. An amputation of the second and third ray of the left hand at the metacarpal level and additionally an axillar revision and lymph node dissection were performed and confirmed the suspicion of a squamous cell carcinoma, fortunately without affection of any lymph nodes. After 9 years the patient showed an excellent function of the left hand. Symbrachydactyly malformations and squamous cell carcinoma of the hand are both rare conditions. We could not find a reference that shows a common genetic condition to both and so far this is the first description of a squamous cell carcinoma in the region of a symbrachydactyly. It remains unclear whether our case is a coincidence of two rare independent diseases or there is a pathogenetic link between the malformation and the tumor on a genetic level.http://dx.doi.org/10.1155/2014/684130 |
| spellingShingle | Tomas Sanchez Daniel Walder Philipp Esenwein Squamous Cell Carcinoma in Combination with a Symbrachydactyly: Initial Management and Long-Term Followup Case Reports in Orthopedics |
| title | Squamous Cell Carcinoma in Combination with a Symbrachydactyly: Initial Management and Long-Term Followup |
| title_full | Squamous Cell Carcinoma in Combination with a Symbrachydactyly: Initial Management and Long-Term Followup |
| title_fullStr | Squamous Cell Carcinoma in Combination with a Symbrachydactyly: Initial Management and Long-Term Followup |
| title_full_unstemmed | Squamous Cell Carcinoma in Combination with a Symbrachydactyly: Initial Management and Long-Term Followup |
| title_short | Squamous Cell Carcinoma in Combination with a Symbrachydactyly: Initial Management and Long-Term Followup |
| title_sort | squamous cell carcinoma in combination with a symbrachydactyly initial management and long term followup |
| url | http://dx.doi.org/10.1155/2014/684130 |
| work_keys_str_mv | AT tomassanchez squamouscellcarcinomaincombinationwithasymbrachydactylyinitialmanagementandlongtermfollowup AT danielwalder squamouscellcarcinomaincombinationwithasymbrachydactylyinitialmanagementandlongtermfollowup AT philippesenwein squamouscellcarcinomaincombinationwithasymbrachydactylyinitialmanagementandlongtermfollowup |