The Relationship between NAFLD and Sarcopenia in Elderly Patients

Aim. Previous studies have shown that individuals with low muscle mass exhibit an increased risk of nonalcoholic fatty liver disease (NAFLD). In this study, we investigated the association between NAFLD and sarcopenia in elderly patients. Methods. We classified the participants into sarcopenia/nonsa...

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Main Authors: Yu Zhai, Qian Xiao, Jing Miao
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Canadian Journal of Gastroenterology and Hepatology
Online Access:http://dx.doi.org/10.1155/2018/5016091
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author Yu Zhai
Qian Xiao
Jing Miao
author_facet Yu Zhai
Qian Xiao
Jing Miao
author_sort Yu Zhai
collection DOAJ
description Aim. Previous studies have shown that individuals with low muscle mass exhibit an increased risk of nonalcoholic fatty liver disease (NAFLD). In this study, we investigated the association between NAFLD and sarcopenia in elderly patients. Methods. We classified the participants into sarcopenia/nonsarcopenia groups based on dual-energy X-ray absorptiometry (DXA), muscle strength (grip strength), or/and physical performance (6 m usual gait speed). We diagnosed NAFLD by ultrasonography combined with the history of alcohol intake. Logistic regression analysis was used to assess the correlation between sarcopenia and NAFLD. Results. NAFLD was significantly less frequent in the sarcopenia group than in the nonsarcopenia group (P<0.01). However, NAFLD was neither an independent risk factor nor a protective factor for sarcopenia. Conclusions. NAFLD is not independently associated with sarcopenia.
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spelling doaj-art-a969cc90427a40cabf694fb92bc6ec7d2025-02-03T05:58:03ZengWileyCanadian Journal of Gastroenterology and Hepatology2291-27892291-27972018-01-01201810.1155/2018/50160915016091The Relationship between NAFLD and Sarcopenia in Elderly PatientsYu Zhai0Qian Xiao1Jing Miao2Department of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, ChinaDepartment of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, ChinaDepartment of Public Health College, Chongqing Medical University, Chongqing 400016, ChinaAim. Previous studies have shown that individuals with low muscle mass exhibit an increased risk of nonalcoholic fatty liver disease (NAFLD). In this study, we investigated the association between NAFLD and sarcopenia in elderly patients. Methods. We classified the participants into sarcopenia/nonsarcopenia groups based on dual-energy X-ray absorptiometry (DXA), muscle strength (grip strength), or/and physical performance (6 m usual gait speed). We diagnosed NAFLD by ultrasonography combined with the history of alcohol intake. Logistic regression analysis was used to assess the correlation between sarcopenia and NAFLD. Results. NAFLD was significantly less frequent in the sarcopenia group than in the nonsarcopenia group (P<0.01). However, NAFLD was neither an independent risk factor nor a protective factor for sarcopenia. Conclusions. NAFLD is not independently associated with sarcopenia.http://dx.doi.org/10.1155/2018/5016091
spellingShingle Yu Zhai
Qian Xiao
Jing Miao
The Relationship between NAFLD and Sarcopenia in Elderly Patients
Canadian Journal of Gastroenterology and Hepatology
title The Relationship between NAFLD and Sarcopenia in Elderly Patients
title_full The Relationship between NAFLD and Sarcopenia in Elderly Patients
title_fullStr The Relationship between NAFLD and Sarcopenia in Elderly Patients
title_full_unstemmed The Relationship between NAFLD and Sarcopenia in Elderly Patients
title_short The Relationship between NAFLD and Sarcopenia in Elderly Patients
title_sort relationship between nafld and sarcopenia in elderly patients
url http://dx.doi.org/10.1155/2018/5016091
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