Calcitonin/Amylin Receptors and Ramps

Our understanding of G protein-coupled receptor function has recently expanded to encompass novel protein interactions that underlie both cell surface receptor expression and the exhibited phenotype. The most notable examples are those involving receptor activity modifying proteins (RAMPs). RAMP ass...

Full description

Saved in:
Bibliographic Details
Main Author: Patrick M. Sexton
Format: Article
Language:English
Published: Wiley 2001-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2001.442
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1841524410482163712
author Patrick M. Sexton
author_facet Patrick M. Sexton
author_sort Patrick M. Sexton
collection DOAJ
description Our understanding of G protein-coupled receptor function has recently expanded to encompass novel protein interactions that underlie both cell surface receptor expression and the exhibited phenotype. The most notable examples are those involving receptor activity modifying proteins (RAMPs). RAMP association with the calcitonin receptor-like receptor (CRLR) traffics this receptor to the cell surface, where individual RAMPs dictate the expression of unique phenotypes.
format Article
id doaj-art-a9682eede0614ca89c4d4642cf5c2755
institution Kabale University
issn 1537-744X
language English
publishDate 2001-01-01
publisher Wiley
record_format Article
series The Scientific World Journal
spelling doaj-art-a9682eede0614ca89c4d4642cf5c27552025-02-03T05:53:22ZengWileyThe Scientific World Journal1537-744X2001-01-0119910.1100/tsw.2001.442Calcitonin/Amylin Receptors and RampsPatrick M. Sexton0Howard Florey Institute of Experimental Physiology and Medicine, The University of Melbourne, Victoria 3010, AustraliaOur understanding of G protein-coupled receptor function has recently expanded to encompass novel protein interactions that underlie both cell surface receptor expression and the exhibited phenotype. The most notable examples are those involving receptor activity modifying proteins (RAMPs). RAMP association with the calcitonin receptor-like receptor (CRLR) traffics this receptor to the cell surface, where individual RAMPs dictate the expression of unique phenotypes.http://dx.doi.org/10.1100/tsw.2001.442
spellingShingle Patrick M. Sexton
Calcitonin/Amylin Receptors and Ramps
The Scientific World Journal
title Calcitonin/Amylin Receptors and Ramps
title_full Calcitonin/Amylin Receptors and Ramps
title_fullStr Calcitonin/Amylin Receptors and Ramps
title_full_unstemmed Calcitonin/Amylin Receptors and Ramps
title_short Calcitonin/Amylin Receptors and Ramps
title_sort calcitonin amylin receptors and ramps
url http://dx.doi.org/10.1100/tsw.2001.442
work_keys_str_mv AT patrickmsexton calcitoninamylinreceptorsandramps