Calcitonin/Amylin Receptors and Ramps
Our understanding of G protein-coupled receptor function has recently expanded to encompass novel protein interactions that underlie both cell surface receptor expression and the exhibited phenotype. The most notable examples are those involving receptor activity modifying proteins (RAMPs). RAMP ass...
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Format: | Article |
Language: | English |
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Wiley
2001-01-01
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Series: | The Scientific World Journal |
Online Access: | http://dx.doi.org/10.1100/tsw.2001.442 |
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author | Patrick M. Sexton |
author_facet | Patrick M. Sexton |
author_sort | Patrick M. Sexton |
collection | DOAJ |
description | Our understanding of G protein-coupled receptor function has recently expanded to encompass novel protein interactions that underlie both cell surface receptor expression and the exhibited phenotype. The most notable examples are those involving receptor activity modifying proteins (RAMPs). RAMP association with the calcitonin receptor-like receptor (CRLR) traffics this receptor to the cell surface, where individual RAMPs dictate the expression of unique phenotypes. |
format | Article |
id | doaj-art-a9682eede0614ca89c4d4642cf5c2755 |
institution | Kabale University |
issn | 1537-744X |
language | English |
publishDate | 2001-01-01 |
publisher | Wiley |
record_format | Article |
series | The Scientific World Journal |
spelling | doaj-art-a9682eede0614ca89c4d4642cf5c27552025-02-03T05:53:22ZengWileyThe Scientific World Journal1537-744X2001-01-0119910.1100/tsw.2001.442Calcitonin/Amylin Receptors and RampsPatrick M. Sexton0Howard Florey Institute of Experimental Physiology and Medicine, The University of Melbourne, Victoria 3010, AustraliaOur understanding of G protein-coupled receptor function has recently expanded to encompass novel protein interactions that underlie both cell surface receptor expression and the exhibited phenotype. The most notable examples are those involving receptor activity modifying proteins (RAMPs). RAMP association with the calcitonin receptor-like receptor (CRLR) traffics this receptor to the cell surface, where individual RAMPs dictate the expression of unique phenotypes.http://dx.doi.org/10.1100/tsw.2001.442 |
spellingShingle | Patrick M. Sexton Calcitonin/Amylin Receptors and Ramps The Scientific World Journal |
title | Calcitonin/Amylin Receptors and Ramps |
title_full | Calcitonin/Amylin Receptors and Ramps |
title_fullStr | Calcitonin/Amylin Receptors and Ramps |
title_full_unstemmed | Calcitonin/Amylin Receptors and Ramps |
title_short | Calcitonin/Amylin Receptors and Ramps |
title_sort | calcitonin amylin receptors and ramps |
url | http://dx.doi.org/10.1100/tsw.2001.442 |
work_keys_str_mv | AT patrickmsexton calcitoninamylinreceptorsandramps |