Photodynamic Therapy (PDT) in drug delivery: Nano-innovations enhancing treatment outcomes
One approach to treating cancer and other infections is Photodynamic Therapy (PDT). Numerous treatment modalities including PDT have long recognized the need to improve the performance of nanoscale therapeutic frameworks. Photosensitizers (Ps) are NPs used in PDT, selectively targeting malignant tis...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-03-01
|
| Series: | Health Sciences Review |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772632025000108 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832087410168561664 |
|---|---|
| author | Ahmed N. Al-Jamal Ali Fawzi Al-Hussainy Bahira Abdulrazzaq Mohammed Hadi Hussein Abbas Issa Mohammed Kadhim Zahraa Hassan Ward Debarshi Kar Mahapatra Tomy Muringayil Joseph Ehsan kianfar Sabu Thomas |
| author_facet | Ahmed N. Al-Jamal Ali Fawzi Al-Hussainy Bahira Abdulrazzaq Mohammed Hadi Hussein Abbas Issa Mohammed Kadhim Zahraa Hassan Ward Debarshi Kar Mahapatra Tomy Muringayil Joseph Ehsan kianfar Sabu Thomas |
| author_sort | Ahmed N. Al-Jamal |
| collection | DOAJ |
| description | One approach to treating cancer and other infections is Photodynamic Therapy (PDT). Numerous treatment modalities including PDT have long recognized the need to improve the performance of nanoscale therapeutic frameworks. Photosensitizers (Ps) are NPs used in PDT, selectively targeting malignant tissues for therapeutic effects, while sparing healthy cells. Using NPs as a carrier might be a great achievement since these NPs have all the necessary components for an ideal PDT operator. The review explores various types of NPs used in PDT. It also depicts the subsequent advancements in the use of inorganic NPs and NPs derived from biodegradable polymers. Varieties of dynamic NPs including those that upconvert, self-radiate, and photosynthesize are now under review. |
| format | Article |
| id | doaj-art-a968208de00e4229b29f611ec7b5f5f4 |
| institution | Kabale University |
| issn | 2772-6320 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Health Sciences Review |
| spelling | doaj-art-a968208de00e4229b29f611ec7b5f5f42025-02-06T05:13:06ZengElsevierHealth Sciences Review2772-63202025-03-0114100218Photodynamic Therapy (PDT) in drug delivery: Nano-innovations enhancing treatment outcomesAhmed N. Al-Jamal0Ali Fawzi Al-Hussainy1Bahira Abdulrazzaq Mohammed2Hadi Hussein Abbas3Issa Mohammed Kadhim4Zahraa Hassan Ward5Debarshi Kar Mahapatra6Tomy Muringayil Joseph7Ehsan kianfar8Sabu Thomas9Department of Biomedical Engineering, College of Engineering, Babylon University, Babylon, IraqCollege of Pharmacy, Ahl Al Bayt University, Kerbala, IraqAl-Hadi University College, Baghdad, 10011, IraqDepartment of Pharmacy, Al-Manara College for Medical Sciences, (Maysan), IraqDepartment of Medical Laboratories Technology, Al-Nisour University College, Nisour Seq. Karkh, Baghdad, IraqMazaya University College, IraqDepartment of Pharmaceutical Chemistry, Shri Rawatpura Sarkar Institute of Pharmacy, Kumhari 490042, Dist. Durg, Chhattisgarh, IndiaDepartment of Polymer Technology, Faculty of Chemistry, Gdańsk University of Technology, G. Narutowicza 11/12 80-233, Gdańsk, Poland; Corresponding authors.Young Researchers and Elite Club, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran; Corresponding authors.Trivandrum Engineering Science & Technology Research Park, TC-4/2322, GEM Building, Sreekariyam, Trivandrum 695016, Kerala, India; Department of Chemical Sciences, University of Johannesburg, Doornfontein, P.O. Box 17011, Johannesburg 2028, South Africa; International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam 686560, Kerala, IndiaOne approach to treating cancer and other infections is Photodynamic Therapy (PDT). Numerous treatment modalities including PDT have long recognized the need to improve the performance of nanoscale therapeutic frameworks. Photosensitizers (Ps) are NPs used in PDT, selectively targeting malignant tissues for therapeutic effects, while sparing healthy cells. Using NPs as a carrier might be a great achievement since these NPs have all the necessary components for an ideal PDT operator. The review explores various types of NPs used in PDT. It also depicts the subsequent advancements in the use of inorganic NPs and NPs derived from biodegradable polymers. Varieties of dynamic NPs including those that upconvert, self-radiate, and photosynthesize are now under review.http://www.sciencedirect.com/science/article/pii/S2772632025000108Light therapyPhotosynthesizeQuantum dotsPhotodynamicTherapy |
| spellingShingle | Ahmed N. Al-Jamal Ali Fawzi Al-Hussainy Bahira Abdulrazzaq Mohammed Hadi Hussein Abbas Issa Mohammed Kadhim Zahraa Hassan Ward Debarshi Kar Mahapatra Tomy Muringayil Joseph Ehsan kianfar Sabu Thomas Photodynamic Therapy (PDT) in drug delivery: Nano-innovations enhancing treatment outcomes Health Sciences Review Light therapy Photosynthesize Quantum dots Photodynamic Therapy |
| title | Photodynamic Therapy (PDT) in drug delivery: Nano-innovations enhancing treatment outcomes |
| title_full | Photodynamic Therapy (PDT) in drug delivery: Nano-innovations enhancing treatment outcomes |
| title_fullStr | Photodynamic Therapy (PDT) in drug delivery: Nano-innovations enhancing treatment outcomes |
| title_full_unstemmed | Photodynamic Therapy (PDT) in drug delivery: Nano-innovations enhancing treatment outcomes |
| title_short | Photodynamic Therapy (PDT) in drug delivery: Nano-innovations enhancing treatment outcomes |
| title_sort | photodynamic therapy pdt in drug delivery nano innovations enhancing treatment outcomes |
| topic | Light therapy Photosynthesize Quantum dots Photodynamic Therapy |
| url | http://www.sciencedirect.com/science/article/pii/S2772632025000108 |
| work_keys_str_mv | AT ahmednaljamal photodynamictherapypdtindrugdeliverynanoinnovationsenhancingtreatmentoutcomes AT alifawzialhussainy photodynamictherapypdtindrugdeliverynanoinnovationsenhancingtreatmentoutcomes AT bahiraabdulrazzaqmohammed photodynamictherapypdtindrugdeliverynanoinnovationsenhancingtreatmentoutcomes AT hadihusseinabbas photodynamictherapypdtindrugdeliverynanoinnovationsenhancingtreatmentoutcomes AT issamohammedkadhim photodynamictherapypdtindrugdeliverynanoinnovationsenhancingtreatmentoutcomes AT zahraahassanward photodynamictherapypdtindrugdeliverynanoinnovationsenhancingtreatmentoutcomes AT debarshikarmahapatra photodynamictherapypdtindrugdeliverynanoinnovationsenhancingtreatmentoutcomes AT tomymuringayiljoseph photodynamictherapypdtindrugdeliverynanoinnovationsenhancingtreatmentoutcomes AT ehsankianfar photodynamictherapypdtindrugdeliverynanoinnovationsenhancingtreatmentoutcomes AT sabuthomas photodynamictherapypdtindrugdeliverynanoinnovationsenhancingtreatmentoutcomes |