How Do Metal Ion Levels Change over Time in Hip Resurfacing Patients? A Cohort Study
Metal-on-metal hip resurfacing (MOM-HR) is offered as an alternative to traditional hip arthroplasty for young, active adults with advanced osteoarthritis. Nevertheless, concerns remain regarding wear and corrosion of the bearing surfaces and the resulting increase in metal ion levels. We evaluated...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2014/291925 |
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| author | Lucia Savarino Matteo Cadossi Eugenio Chiarello Caterina Fotia Michelina Greco Nicola Baldini Sandro Giannini |
| author_facet | Lucia Savarino Matteo Cadossi Eugenio Chiarello Caterina Fotia Michelina Greco Nicola Baldini Sandro Giannini |
| author_sort | Lucia Savarino |
| collection | DOAJ |
| description | Metal-on-metal hip resurfacing (MOM-HR) is offered as an alternative to traditional hip arthroplasty for young, active adults with advanced osteoarthritis. Nevertheless, concerns remain regarding wear and corrosion of the bearing surfaces and the resulting increase in metal ion levels. We evaluated three cohorts of patients with Birmingham hip resurfacing (BHR) at an average follow-up of 2, 5, and 9 years. We asked whether there would be differences in ion levels between the cohorts and inside the gender. Nineteen patients were prospectively analyzed. The correlation with clinical-radiographic data was also performed. Chromium, cobalt, nickel, and molybdenum concentrations were measured by atomic absorption spectrophotometry.
Chromium and cobalt levels demonstrated a tendency to decrease over time. Such tendency was present only in females. An inverse correlation between chromium, implant size, and Harris hip score was present at short term; it disappeared over time together with the decreased ion levels. The prospective analysis showed that, although metal ion levels remained fairly constant within each patient, there was a relatively large variation between subjects, so mean data in this scenario must be interpreted with caution.
The chronic high exposure should be carefully considered during implant selection, particularly in young subjects, and a stricter monitoring is mandatory. |
| format | Article |
| id | doaj-art-a967664fc2734e3f936e3e40e293f6bb |
| institution | OA Journals |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-a967664fc2734e3f936e3e40e293f6bb2025-08-20T02:23:07ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/291925291925How Do Metal Ion Levels Change over Time in Hip Resurfacing Patients? A Cohort StudyLucia Savarino0Matteo Cadossi1Eugenio Chiarello2Caterina Fotia3Michelina Greco4Nicola Baldini5Sandro Giannini6Laboratory for Orthopaedic Pathophysiology and Regenerative Medicine, Rizzoli Orthopaedic Institute, Via di Barbiano 1/10, 40136 Bologna, ItalyDepartment I of Orthopaedics and Traumatology, Rizzoli Orthopaedic Institute, Via Pupilli 1, 40136 Bologna, ItalyDepartment I of Orthopaedics and Traumatology, Rizzoli Orthopaedic Institute, Via Pupilli 1, 40136 Bologna, ItalyLaboratory for Orthopaedic Pathophysiology and Regenerative Medicine, Rizzoli Orthopaedic Institute, Via di Barbiano 1/10, 40136 Bologna, ItalyLaboratory for Orthopaedic Pathophysiology and Regenerative Medicine, Rizzoli Orthopaedic Institute, Via di Barbiano 1/10, 40136 Bologna, ItalyLaboratory for Orthopaedic Pathophysiology and Regenerative Medicine, Rizzoli Orthopaedic Institute, Via di Barbiano 1/10, 40136 Bologna, ItalyDepartment I of Orthopaedics and Traumatology, Rizzoli Orthopaedic Institute, Via Pupilli 1, 40136 Bologna, ItalyMetal-on-metal hip resurfacing (MOM-HR) is offered as an alternative to traditional hip arthroplasty for young, active adults with advanced osteoarthritis. Nevertheless, concerns remain regarding wear and corrosion of the bearing surfaces and the resulting increase in metal ion levels. We evaluated three cohorts of patients with Birmingham hip resurfacing (BHR) at an average follow-up of 2, 5, and 9 years. We asked whether there would be differences in ion levels between the cohorts and inside the gender. Nineteen patients were prospectively analyzed. The correlation with clinical-radiographic data was also performed. Chromium, cobalt, nickel, and molybdenum concentrations were measured by atomic absorption spectrophotometry. Chromium and cobalt levels demonstrated a tendency to decrease over time. Such tendency was present only in females. An inverse correlation between chromium, implant size, and Harris hip score was present at short term; it disappeared over time together with the decreased ion levels. The prospective analysis showed that, although metal ion levels remained fairly constant within each patient, there was a relatively large variation between subjects, so mean data in this scenario must be interpreted with caution. The chronic high exposure should be carefully considered during implant selection, particularly in young subjects, and a stricter monitoring is mandatory.http://dx.doi.org/10.1155/2014/291925 |
| spellingShingle | Lucia Savarino Matteo Cadossi Eugenio Chiarello Caterina Fotia Michelina Greco Nicola Baldini Sandro Giannini How Do Metal Ion Levels Change over Time in Hip Resurfacing Patients? A Cohort Study The Scientific World Journal |
| title | How Do Metal Ion Levels Change over Time in Hip Resurfacing Patients? A Cohort Study |
| title_full | How Do Metal Ion Levels Change over Time in Hip Resurfacing Patients? A Cohort Study |
| title_fullStr | How Do Metal Ion Levels Change over Time in Hip Resurfacing Patients? A Cohort Study |
| title_full_unstemmed | How Do Metal Ion Levels Change over Time in Hip Resurfacing Patients? A Cohort Study |
| title_short | How Do Metal Ion Levels Change over Time in Hip Resurfacing Patients? A Cohort Study |
| title_sort | how do metal ion levels change over time in hip resurfacing patients a cohort study |
| url | http://dx.doi.org/10.1155/2014/291925 |
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