Clinical Usefulness of Response Profiles to Rapidly Incremental Cardiopulmonary Exercise Testing
The advent of microprocessed “metabolic carts” and rapidly incremental protocols greatly expanded the clinical applications of cardiopulmonary exercise testing (CPET). The response normalcy to CPET is more commonly appreciated at discrete time points, for example, at the estimated lactate threshold...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Pulmonary Medicine |
| Online Access: | http://dx.doi.org/10.1155/2013/359021 |
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| author | Roberta P. Ramos Maria Clara N. Alencar Erika Treptow Flávio Arbex Eloara M. V. Ferreira J. Alberto Neder |
| author_facet | Roberta P. Ramos Maria Clara N. Alencar Erika Treptow Flávio Arbex Eloara M. V. Ferreira J. Alberto Neder |
| author_sort | Roberta P. Ramos |
| collection | DOAJ |
| description | The advent of microprocessed “metabolic carts” and rapidly incremental protocols greatly expanded the clinical applications of cardiopulmonary exercise testing (CPET). The response normalcy to CPET is more commonly appreciated at discrete time points, for example, at the estimated lactate threshold and at peak exercise. Analysis of the response profiles of cardiopulmonary responses at submaximal exercise and recovery, however, might show abnormal physiologic functioning which would not be otherwise unraveled. Although this approach has long been advocated as a key element of the investigational strategy, it remains largely neglected in practice. The purpose of this paper, therefore, is to highlight the usefulness of selected submaximal metabolic, ventilatory, and cardiovascular variables in different clinical scenarios and patient populations. Special care is taken to physiologically justify their use to answer pertinent clinical questions and to the technical aspects that should be observed to improve responses’ reproducibility and reliability. The most recent evidence in favor of (and against) these variables for diagnosis, impairment evaluation, and prognosis in systemic diseases is also critically discussed. |
| format | Article |
| id | doaj-art-a965e3b5e670435dbb300b34f5b02c3d |
| institution | Kabale University |
| issn | 2090-1836 2090-1844 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pulmonary Medicine |
| spelling | doaj-art-a965e3b5e670435dbb300b34f5b02c3d2025-08-20T03:39:10ZengWileyPulmonary Medicine2090-18362090-18442013-01-01201310.1155/2013/359021359021Clinical Usefulness of Response Profiles to Rapidly Incremental Cardiopulmonary Exercise TestingRoberta P. Ramos0Maria Clara N. Alencar1Erika Treptow2Flávio Arbex3Eloara M. V. Ferreira4J. Alberto Neder5Pulmonary Function and Clinical Exercise Physiology Unit (SEFICE), Division of Respiratory Diseases, Department of Medicine, Federal University of Sao Paulo (UNIFESP), Rua Francisco de Castro 54, Vila Mariana, 04020-050 São Paulo, SP, BrazilPulmonary Function and Clinical Exercise Physiology Unit (SEFICE), Division of Respiratory Diseases, Department of Medicine, Federal University of Sao Paulo (UNIFESP), Rua Francisco de Castro 54, Vila Mariana, 04020-050 São Paulo, SP, BrazilPulmonary Function and Clinical Exercise Physiology Unit (SEFICE), Division of Respiratory Diseases, Department of Medicine, Federal University of Sao Paulo (UNIFESP), Rua Francisco de Castro 54, Vila Mariana, 04020-050 São Paulo, SP, BrazilPulmonary Function and Clinical Exercise Physiology Unit (SEFICE), Division of Respiratory Diseases, Department of Medicine, Federal University of Sao Paulo (UNIFESP), Rua Francisco de Castro 54, Vila Mariana, 04020-050 São Paulo, SP, BrazilPulmonary Function and Clinical Exercise Physiology Unit (SEFICE), Division of Respiratory Diseases, Department of Medicine, Federal University of Sao Paulo (UNIFESP), Rua Francisco de Castro 54, Vila Mariana, 04020-050 São Paulo, SP, BrazilPulmonary Function and Clinical Exercise Physiology Unit (SEFICE), Division of Respiratory Diseases, Department of Medicine, Federal University of Sao Paulo (UNIFESP), Rua Francisco de Castro 54, Vila Mariana, 04020-050 São Paulo, SP, BrazilThe advent of microprocessed “metabolic carts” and rapidly incremental protocols greatly expanded the clinical applications of cardiopulmonary exercise testing (CPET). The response normalcy to CPET is more commonly appreciated at discrete time points, for example, at the estimated lactate threshold and at peak exercise. Analysis of the response profiles of cardiopulmonary responses at submaximal exercise and recovery, however, might show abnormal physiologic functioning which would not be otherwise unraveled. Although this approach has long been advocated as a key element of the investigational strategy, it remains largely neglected in practice. The purpose of this paper, therefore, is to highlight the usefulness of selected submaximal metabolic, ventilatory, and cardiovascular variables in different clinical scenarios and patient populations. Special care is taken to physiologically justify their use to answer pertinent clinical questions and to the technical aspects that should be observed to improve responses’ reproducibility and reliability. The most recent evidence in favor of (and against) these variables for diagnosis, impairment evaluation, and prognosis in systemic diseases is also critically discussed.http://dx.doi.org/10.1155/2013/359021 |
| spellingShingle | Roberta P. Ramos Maria Clara N. Alencar Erika Treptow Flávio Arbex Eloara M. V. Ferreira J. Alberto Neder Clinical Usefulness of Response Profiles to Rapidly Incremental Cardiopulmonary Exercise Testing Pulmonary Medicine |
| title | Clinical Usefulness of Response Profiles to Rapidly Incremental Cardiopulmonary Exercise Testing |
| title_full | Clinical Usefulness of Response Profiles to Rapidly Incremental Cardiopulmonary Exercise Testing |
| title_fullStr | Clinical Usefulness of Response Profiles to Rapidly Incremental Cardiopulmonary Exercise Testing |
| title_full_unstemmed | Clinical Usefulness of Response Profiles to Rapidly Incremental Cardiopulmonary Exercise Testing |
| title_short | Clinical Usefulness of Response Profiles to Rapidly Incremental Cardiopulmonary Exercise Testing |
| title_sort | clinical usefulness of response profiles to rapidly incremental cardiopulmonary exercise testing |
| url | http://dx.doi.org/10.1155/2013/359021 |
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