Causal analysis and impact of a systematic error detected about consumption associated with trastuzumab

Objective: determine the cause of the constant difference between the theoretical and real number of trastuzumab units consumed in an Intravenous Mixtures Unit. Methods: was studied the manual and electronic full procedure about preparing mixtures with trastuzumab. Was performed by visual observat...

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Main Authors: Nuria Bujaldón Querejeta, Dolores Camacho Romera, José Antonio Pomares Pastor, María Sánchez Garnes, Mauricio Martínez Ramírez, Mercedes González Delgado
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Farmacia Hospitalaria
Subjects:
Online Access:http://www.aulamedica.es/fh/pdf/8406.pdf
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author Nuria Bujaldón Querejeta
Dolores Camacho Romera
José Antonio Pomares Pastor
María Sánchez Garnes
Mauricio Martínez Ramírez
Mercedes González Delgado
author_facet Nuria Bujaldón Querejeta
Dolores Camacho Romera
José Antonio Pomares Pastor
María Sánchez Garnes
Mauricio Martínez Ramírez
Mercedes González Delgado
author_sort Nuria Bujaldón Querejeta
collection DOAJ
description Objective: determine the cause of the constant difference between the theoretical and real number of trastuzumab units consumed in an Intravenous Mixtures Unit. Methods: was studied the manual and electronic full procedure about preparing mixtures with trastuzumab. Was performed by visual observation and review of quantitative monitoring data from the electronic preparation support and safe system of the application Farmis-Oncofarm®. Results: difference between the optimum volume of trastuzumab contained in the summary of product characteristics and the same included in Farmis_Oncofarm® was found. Also found a defect of the optimum volume of 10ml syringes used in the reconstitution vials process. Conclusions: the default in the optimal volume of 10ml syringes used in the reconstitution process increases the real consumed units of trastuzumab. This produces a significant economic impact calculated in an annual additional cost in approximately 46.508 € without negative consequences for the patient
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language English
publishDate 2015-09-01
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series Farmacia Hospitalaria
spelling doaj-art-a95d07f736d14c3fb33550a8f03bdb872025-08-20T02:18:04ZengElsevierFarmacia Hospitalaria1130-63432171-86952015-09-0139530931310.7399/fh.2015.39.5.8406Causal analysis and impact of a systematic error detected about consumption associated with trastuzumabNuria Bujaldón Querejeta0Dolores Camacho Romera1José Antonio Pomares Pastor2María Sánchez Garnes3Mauricio Martínez Ramírez4Mercedes González Delgado5Servicio de Farmacia Hospital Universitario Sant Joan, Alicante. EspañaServicio de Farmacia Hospital Universitario Sant Joan, Alicante. España.Servicio de Farmacia Hospital Universitario Sant Joan, Alicante. España.Servicio de Farmacia Hospital Universitario Sant Joan, Alicante. España.Servicio de Farmacia Hospital Universitario Sant Joan, Alicante. España.Servicio de Farmacia Hospital Universitario Sant Joan, Alicante. España.Objective: determine the cause of the constant difference between the theoretical and real number of trastuzumab units consumed in an Intravenous Mixtures Unit. Methods: was studied the manual and electronic full procedure about preparing mixtures with trastuzumab. Was performed by visual observation and review of quantitative monitoring data from the electronic preparation support and safe system of the application Farmis-Oncofarm®. Results: difference between the optimum volume of trastuzumab contained in the summary of product characteristics and the same included in Farmis_Oncofarm® was found. Also found a defect of the optimum volume of 10ml syringes used in the reconstitution vials process. Conclusions: the default in the optimal volume of 10ml syringes used in the reconstitution process increases the real consumed units of trastuzumab. This produces a significant economic impact calculated in an annual additional cost in approximately 46.508 € without negative consequences for the patienthttp://www.aulamedica.es/fh/pdf/8406.pdfElectronic prescription system; DefaultSyringe; PreparationDrug
spellingShingle Nuria Bujaldón Querejeta
Dolores Camacho Romera
José Antonio Pomares Pastor
María Sánchez Garnes
Mauricio Martínez Ramírez
Mercedes González Delgado
Causal analysis and impact of a systematic error detected about consumption associated with trastuzumab
Farmacia Hospitalaria
Electronic prescription system
; Default
Syringe
; Preparation
Drug
title Causal analysis and impact of a systematic error detected about consumption associated with trastuzumab
title_full Causal analysis and impact of a systematic error detected about consumption associated with trastuzumab
title_fullStr Causal analysis and impact of a systematic error detected about consumption associated with trastuzumab
title_full_unstemmed Causal analysis and impact of a systematic error detected about consumption associated with trastuzumab
title_short Causal analysis and impact of a systematic error detected about consumption associated with trastuzumab
title_sort causal analysis and impact of a systematic error detected about consumption associated with trastuzumab
topic Electronic prescription system
; Default
Syringe
; Preparation
Drug
url http://www.aulamedica.es/fh/pdf/8406.pdf
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