Effect of different maneuvers of repositioning on benign paroxysmal vertigo: a network meta-analysis

Abstract Background The effect of different maneuver repositioning on benign paroxysmal vertigo was explored by network meta-analysis. Methods The PubMed, Embase, Cochrane library, and web of science databases were searched for randomized controlled studies on the effect of manipulative repositionin...

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Bibliographic Details
Main Authors: Nannan Si, MengYuan Liu, Wei Chang
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Neurology
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Online Access:https://doi.org/10.1186/s12883-025-04123-6
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Summary:Abstract Background The effect of different maneuver repositioning on benign paroxysmal vertigo was explored by network meta-analysis. Methods The PubMed, Embase, Cochrane library, and web of science databases were searched for randomized controlled studies on the effect of manipulative repositioning on benign paroxysmal vertigo from database creation to September 1, 2024, Bayesian network meta-analysis, R4.4.1 was used for data analysis. Results Twenty-two articles (n = 2507) were included in this study, and the results of network meta-analysis suggested the following odds ratios (OR) relative to the control group (UT): Epley maneuver (EM) vs UT [OR = 7.9, 95% CI (3.21, 23.31)]; Gufoni maneuver (GFM) vs UT [OR = 5.1, 95% CI (1.25, 21.45)]; Gans Repositioning Maneuvers (GRM) vs UT [OR = 11, 95% CI (1.65, 83.85)]; Modified Epley maneuver (MEM) vs UT [OR = 9.83, 95% CI (1.55, 64.06)]; Semont’s maneuver (SM) vs UT [OR = 6.1, 95% CI (1.97, 18.46)]. The largest surface area under the cumulative ranking curve was for GRM (71.5%), followed by MEM (68%) and SEM (67.8%), and the worst was for UT (5.7%). Conclusion Based on our current findings, GRM, MEM and SEM are effective for BBPV symptoms, but due to the existence of study limitations, more high quality multicenter large sample randomized controlled studies are needed to testify to our conclusions.
ISSN:1471-2377