Cross-species transcriptome-wide meta-analysis of anterior cruciate ligament rupture

Cross-species transcriptome-wide meta-analysis of anterior cruciate ligament rupture

Abstract Background The Anterior Cruciate Ligament (ACL) plays a critical role in maintaining the musculoskeletal stability of the knee. Its injury has been linked to an increased risk of developing osteoarthritis. This study aims to identify cross-species responses to ACL rupture providing insights...

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Bibliographic Details
Main Authors: Livia Beccacece, Stefano Pallotti, Yiyun Li, Jie Huang, Leonardo Pasotti, Valerio Napolioni
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Genomics
Subjects:
Anterior cruciate ligament rupture
Transcriptomics
Cross-species meta-analysis
Translational genomics
Online Access:https://doi.org/10.1186/s12864-025-11702-x
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