Deciphering the preeclampsia-specific immune microenvironment and the role of pro-inflammatory macrophages at the maternal–fetal interface

Deciphering the preeclampsia-specific immune microenvironment and the role of pro-inflammatory macrophages at the maternal–fetal interface

Preeclampsia (PE), a major cause of maternal and perinatal mortality with highly heterogeneous causes and symptoms, is usually complicated by gestational diabetes mellitus (GDM). However, a comprehensive understanding of the immune microenvironment in the placenta of PE and the differences between P...

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Bibliographic Details
Main Authors: Haiyi Fei, Xiaowen Lu, Zhan Shi, Xiu Liu, Cuiyu Yang, Xiaohong Zhu, Yuhan Lin, Ziqun Jiang, Jianmin Wang, Dong Huang, Liu Liu, Songying Zhang, Lingling Jiang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-03-01
Series:eLife
Subjects:
preeclampsia
maternal–fetal immunity
CyTOF
scRNA sequencing
macrophages
Online Access:https://elifesciences.org/articles/100002
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