Stem cell therapy for regenerating periodontal bony defects: A narrative review
Periodontal bony defects pose a significant challenge in periodontology, necessitating advanced regenerative approaches to restore the lost structures. Stem cell-based therapies have emerged as a promising solution due to their ability to differentiate into various cells, modulating the regenerative...
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| Format: | Article |
| Language: | English |
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Tabriz University of Medical Sciences
2025-03-01
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| Series: | Journal of Advanced Periodontology and Implant Dentistry |
| Subjects: | |
| Online Access: | https://japid.tbzmed.ac.ir/PDF/japid-17-1.pdf |
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| _version_ | 1850183877935497216 |
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| author | Samira Mohammad Mirzapour Fatemeh Jalali |
| author_facet | Samira Mohammad Mirzapour Fatemeh Jalali |
| author_sort | Samira Mohammad Mirzapour |
| collection | DOAJ |
| description | Periodontal bony defects pose a significant challenge in periodontology, necessitating advanced regenerative approaches to restore the lost structures. Stem cell-based therapies have emerged as a promising solution due to their ability to differentiate into various cells, modulating the regenerative microenvironment. This narrative review explores the potential of stem cells derived from multiple sources in treating periodontal bony defects. Additionally, we examine evidence from both animal and human studies, highlighting advancements, clinical outcomes, and limitations. By investigating these findings, this article provides a comprehensive overview of the advantages of stem cell-based therapies compared to other regenerative techniques in addressing periodontal bony defects and discusses the limitations of their translation into routine clinical practice. |
| format | Article |
| id | doaj-art-a943bd19c4d24b498d8744a6a03fcbbe |
| institution | OA Journals |
| issn | 2645-5390 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Journal of Advanced Periodontology and Implant Dentistry |
| spelling | doaj-art-a943bd19c4d24b498d8744a6a03fcbbe2025-08-20T02:17:13ZengTabriz University of Medical SciencesJournal of Advanced Periodontology and Implant Dentistry2645-53902025-03-0117111410.34172/japid.025.3749japid-3749Stem cell therapy for regenerating periodontal bony defects: A narrative reviewSamira Mohammad Mirzapour0Fatemeh Jalali1Department of Periodontics, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, IranStudent Research Committee, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, IranPeriodontal bony defects pose a significant challenge in periodontology, necessitating advanced regenerative approaches to restore the lost structures. Stem cell-based therapies have emerged as a promising solution due to their ability to differentiate into various cells, modulating the regenerative microenvironment. This narrative review explores the potential of stem cells derived from multiple sources in treating periodontal bony defects. Additionally, we examine evidence from both animal and human studies, highlighting advancements, clinical outcomes, and limitations. By investigating these findings, this article provides a comprehensive overview of the advantages of stem cell-based therapies compared to other regenerative techniques in addressing periodontal bony defects and discusses the limitations of their translation into routine clinical practice.https://japid.tbzmed.ac.ir/PDF/japid-17-1.pdfperiodontitisregenerationreviewstem cells |
| spellingShingle | Samira Mohammad Mirzapour Fatemeh Jalali Stem cell therapy for regenerating periodontal bony defects: A narrative review Journal of Advanced Periodontology and Implant Dentistry periodontitis regeneration review stem cells |
| title | Stem cell therapy for regenerating periodontal bony defects: A narrative review |
| title_full | Stem cell therapy for regenerating periodontal bony defects: A narrative review |
| title_fullStr | Stem cell therapy for regenerating periodontal bony defects: A narrative review |
| title_full_unstemmed | Stem cell therapy for regenerating periodontal bony defects: A narrative review |
| title_short | Stem cell therapy for regenerating periodontal bony defects: A narrative review |
| title_sort | stem cell therapy for regenerating periodontal bony defects a narrative review |
| topic | periodontitis regeneration review stem cells |
| url | https://japid.tbzmed.ac.ir/PDF/japid-17-1.pdf |
| work_keys_str_mv | AT samiramohammadmirzapour stemcelltherapyforregeneratingperiodontalbonydefectsanarrativereview AT fatemehjalali stemcelltherapyforregeneratingperiodontalbonydefectsanarrativereview |