Monte Carlo approximation of the logarithm of the determinant of large matrices with applications for linear mixed models in quantitative genetics

Abstract Background Likelihood-based inferences such as variance components estimation and hypothesis testing need logarithms of the determinant (log-determinant) of high dimensional matrices. Calculating the log-determinant is memory and time-consuming, making it impossible to perform likelihood-ba...

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Bibliographic Details
Main Authors: Matias Bermann, Alejandra Alvarez-Munera, Andres Legarra, Ignacio Aguilar, Ignacy Misztal, Daniela Lourenco
Format: Article
Language:deu
Published: BMC 2025-08-01
Series:Genetics Selection Evolution
Online Access:https://doi.org/10.1186/s12711-025-00991-1
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