Effects of dietary nano-selenium on the growth performance, antioxidant capacity, immunity and intestinal microbiota of Tibetan naked carp (Gymnocypris przewalskii)

This study aimed to investigate the effects of nano-selenium (nano-se) as a dietary supplement on Tibetan naked carp (Gymnocypris przewalskii) and six separate groups were conducted (0 mg/kg, NSEC; 2 mg/kg, NSE2; 4 mg/kg, NSE4; 7 mg/kg, NSE7; 9 mg/kg, NSE9; and 11 mg/kg, NSE11). The growth performan...

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Main Authors: Yanxia Chen, Caixia He, Ying Yang, Linan Wang, Zhaonan Li, Qingchun Yan, Tianxiu Liang, Changhong Bao, Wenjie Jin, Changzhong Li
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Aquaculture Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352513424005192
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author Yanxia Chen
Caixia He
Ying Yang
Linan Wang
Zhaonan Li
Qingchun Yan
Tianxiu Liang
Changhong Bao
Wenjie Jin
Changzhong Li
author_facet Yanxia Chen
Caixia He
Ying Yang
Linan Wang
Zhaonan Li
Qingchun Yan
Tianxiu Liang
Changhong Bao
Wenjie Jin
Changzhong Li
author_sort Yanxia Chen
collection DOAJ
description This study aimed to investigate the effects of nano-selenium (nano-se) as a dietary supplement on Tibetan naked carp (Gymnocypris przewalskii) and six separate groups were conducted (0 mg/kg, NSEC; 2 mg/kg, NSE2; 4 mg/kg, NSE4; 7 mg/kg, NSE7; 9 mg/kg, NSE9; and 11 mg/kg, NSE11). The growth performance, hemato-biochemical activity, antioxidant activity, immune indices, and intestinal microbiota were subsequently measured at the end of the feeding experiment. The results showed that the hepatosomatic index, viscerosomatic index and condition factor were significantly greater in the NSE4 group (P < 0.05). The NSE4 group presented the highest specific growth rate and weight gain rate, whereas the NSE11 group presented the lowest rates. The survival rate was greater in the NSE2, NSE4, and NSE9 groups, whereas it was lowest in the NSE11 group. The contents of TP and TG and the activities of T-AOC, GSH-Px, T-SOD, CAT and GR first increased but then decreased with increasing dietary selenium content. Compared with the other groups, the NSE4 group presented comparatively lower levels of proinflammatory factors such as IL-1β, IL-6, and TNF-α, but higher amounts of lysozyme LZM and immunoglobulin IgM. The NSE4 and NSE2 groups presented considerably increased levels of anti-inflammatory factors (IL-10 and TGF-β) (P < 0.05). Dietary supplementation with an appropriate amount of nano-se can improve liver vacuolationand hepatocyte swelling in G. przewalskii, but excessive nano-se could cause liver damage. In addition, the results of intestinal microbiota detection revealed that dietary nano-se could improve the diversity of the intestinal microbiota and increase the abundance of beneficial bacteria in G. przewalskii. This research will enhance our understanding of the possible uses of nano-se and lay the groundwork for increasing the resource efficiency of G. przewalskii breeding and releasing.
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spelling doaj-art-a937dc6e9e3d4e478e998f45ece61b082025-08-20T02:51:30ZengElsevierAquaculture Reports2352-51342024-12-013910243110.1016/j.aqrep.2024.102431Effects of dietary nano-selenium on the growth performance, antioxidant capacity, immunity and intestinal microbiota of Tibetan naked carp (Gymnocypris przewalskii)Yanxia Chen0Caixia He1Ying Yang2Linan Wang3Zhaonan Li4Qingchun Yan5Tianxiu Liang6Changhong Bao7Wenjie Jin8Changzhong Li9College of Eco-Environmental Engineering, Qinghai University, No. 251 Ningda Road, Xining 810016, China; Key Laboratory of Plateau Cold-water Fish Culture and Eco-environmental Conservation (Co-construction by Ministry and Province), Ministry of Agriculture and Rural Affairs, No. 251 Ningda Road, Xining 810016, Qinghai, China; Corresponding authors at: College of Eco-Environmental Engineering, Qinghai University, No. 251 Ningda Road, Xining 810016, China.College of Eco-Environmental Engineering, Qinghai University, No. 251 Ningda Road, Xining 810016, China; Key Laboratory of Plateau Cold-water Fish Culture and Eco-environmental Conservation (Co-construction by Ministry and Province), Ministry of Agriculture and Rural Affairs, No. 251 Ningda Road, Xining 810016, Qinghai, ChinaCollege of Eco-Environmental Engineering, Qinghai University, No. 251 Ningda Road, Xining 810016, China; Key Laboratory of Plateau Cold-water Fish Culture and Eco-environmental Conservation (Co-construction by Ministry and Province), Ministry of Agriculture and Rural Affairs, No. 251 Ningda Road, Xining 810016, Qinghai, ChinaCollege of Eco-Environmental Engineering, Qinghai University, No. 251 Ningda Road, Xining 810016, China; Key Laboratory of Plateau Cold-water Fish Culture and Eco-environmental Conservation (Co-construction by Ministry and Province), Ministry of Agriculture and Rural Affairs, No. 251 Ningda Road, Xining 810016, Qinghai, ChinaCollege of Eco-Environmental Engineering, Qinghai University, No. 251 Ningda Road, Xining 810016, China; Key Laboratory of Plateau Cold-water Fish Culture and Eco-environmental Conservation (Co-construction by Ministry and Province), Ministry of Agriculture and Rural Affairs, No. 251 Ningda Road, Xining 810016, Qinghai, ChinaCollege of Eco-Environmental Engineering, Qinghai University, No. 251 Ningda Road, Xining 810016, China; Key Laboratory of Plateau Cold-water Fish Culture and Eco-environmental Conservation (Co-construction by Ministry and Province), Ministry of Agriculture and Rural Affairs, No. 251 Ningda Road, Xining 810016, Qinghai, ChinaCollege of Eco-Environmental Engineering, Qinghai University, No. 251 Ningda Road, Xining 810016, China; Key Laboratory of Plateau Cold-water Fish Culture and Eco-environmental Conservation (Co-construction by Ministry and Province), Ministry of Agriculture and Rural Affairs, No. 251 Ningda Road, Xining 810016, Qinghai, ChinaCollege of Eco-Environmental Engineering, Qinghai University, No. 251 Ningda Road, Xining 810016, China; Key Laboratory of Plateau Cold-water Fish Culture and Eco-environmental Conservation (Co-construction by Ministry and Province), Ministry of Agriculture and Rural Affairs, No. 251 Ningda Road, Xining 810016, Qinghai, ChinaCollege of Eco-Environmental Engineering, Qinghai University, No. 251 Ningda Road, Xining 810016, China; Key Laboratory of Plateau Cold-water Fish Culture and Eco-environmental Conservation (Co-construction by Ministry and Province), Ministry of Agriculture and Rural Affairs, No. 251 Ningda Road, Xining 810016, Qinghai, ChinaCollege of Eco-Environmental Engineering, Qinghai University, No. 251 Ningda Road, Xining 810016, China; Key Laboratory of Plateau Cold-water Fish Culture and Eco-environmental Conservation (Co-construction by Ministry and Province), Ministry of Agriculture and Rural Affairs, No. 251 Ningda Road, Xining 810016, Qinghai, China; Corresponding authors at: College of Eco-Environmental Engineering, Qinghai University, No. 251 Ningda Road, Xining 810016, China.This study aimed to investigate the effects of nano-selenium (nano-se) as a dietary supplement on Tibetan naked carp (Gymnocypris przewalskii) and six separate groups were conducted (0 mg/kg, NSEC; 2 mg/kg, NSE2; 4 mg/kg, NSE4; 7 mg/kg, NSE7; 9 mg/kg, NSE9; and 11 mg/kg, NSE11). The growth performance, hemato-biochemical activity, antioxidant activity, immune indices, and intestinal microbiota were subsequently measured at the end of the feeding experiment. The results showed that the hepatosomatic index, viscerosomatic index and condition factor were significantly greater in the NSE4 group (P < 0.05). The NSE4 group presented the highest specific growth rate and weight gain rate, whereas the NSE11 group presented the lowest rates. The survival rate was greater in the NSE2, NSE4, and NSE9 groups, whereas it was lowest in the NSE11 group. The contents of TP and TG and the activities of T-AOC, GSH-Px, T-SOD, CAT and GR first increased but then decreased with increasing dietary selenium content. Compared with the other groups, the NSE4 group presented comparatively lower levels of proinflammatory factors such as IL-1β, IL-6, and TNF-α, but higher amounts of lysozyme LZM and immunoglobulin IgM. The NSE4 and NSE2 groups presented considerably increased levels of anti-inflammatory factors (IL-10 and TGF-β) (P < 0.05). Dietary supplementation with an appropriate amount of nano-se can improve liver vacuolationand hepatocyte swelling in G. przewalskii, but excessive nano-se could cause liver damage. In addition, the results of intestinal microbiota detection revealed that dietary nano-se could improve the diversity of the intestinal microbiota and increase the abundance of beneficial bacteria in G. przewalskii. This research will enhance our understanding of the possible uses of nano-se and lay the groundwork for increasing the resource efficiency of G. przewalskii breeding and releasing.http://www.sciencedirect.com/science/article/pii/S2352513424005192Gymnocypris przewalskiiFeed additivesAntioxidant capacityImmune responseIntestinal health
spellingShingle Yanxia Chen
Caixia He
Ying Yang
Linan Wang
Zhaonan Li
Qingchun Yan
Tianxiu Liang
Changhong Bao
Wenjie Jin
Changzhong Li
Effects of dietary nano-selenium on the growth performance, antioxidant capacity, immunity and intestinal microbiota of Tibetan naked carp (Gymnocypris przewalskii)
Aquaculture Reports
Gymnocypris przewalskii
Feed additives
Antioxidant capacity
Immune response
Intestinal health
title Effects of dietary nano-selenium on the growth performance, antioxidant capacity, immunity and intestinal microbiota of Tibetan naked carp (Gymnocypris przewalskii)
title_full Effects of dietary nano-selenium on the growth performance, antioxidant capacity, immunity and intestinal microbiota of Tibetan naked carp (Gymnocypris przewalskii)
title_fullStr Effects of dietary nano-selenium on the growth performance, antioxidant capacity, immunity and intestinal microbiota of Tibetan naked carp (Gymnocypris przewalskii)
title_full_unstemmed Effects of dietary nano-selenium on the growth performance, antioxidant capacity, immunity and intestinal microbiota of Tibetan naked carp (Gymnocypris przewalskii)
title_short Effects of dietary nano-selenium on the growth performance, antioxidant capacity, immunity and intestinal microbiota of Tibetan naked carp (Gymnocypris przewalskii)
title_sort effects of dietary nano selenium on the growth performance antioxidant capacity immunity and intestinal microbiota of tibetan naked carp gymnocypris przewalskii
topic Gymnocypris przewalskii
Feed additives
Antioxidant capacity
Immune response
Intestinal health
url http://www.sciencedirect.com/science/article/pii/S2352513424005192
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