Post lung-transplant predictive value of thermodilution vs estimated Fick cardiac output measurement
Background: Comparison of thermodilution (TD) and indirect Fick (iFick) methods of cardiac output (CO) measurement has not been well described in patients with World Health Organization (WHO) group 3 pulmonary hypertension (PH). Methods: We conducted a single-center retrospective chart review of 96...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-05-01
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| Series: | JHLT Open |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2950133425000230 |
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| Summary: | Background: Comparison of thermodilution (TD) and indirect Fick (iFick) methods of cardiac output (CO) measurement has not been well described in patients with World Health Organization (WHO) group 3 pulmonary hypertension (PH). Methods: We conducted a single-center retrospective chart review of 96 patients with WHO group 3 PH who underwent lung transplantation. For comparison, 32 WHO group 1 pulmonary arterial hypertension patients who were followed in our PH clinic during the same period were also included in the study. Results: TThere was a significant difference between iFick CO and TD CO (5.93+/ -1.5 versus 5.46+/ -1.8 liter/minute, p=0.0061) in WHO group 3 PH. Pulmonary vascular resistance (PVR) calculated using iFick and TD–CO values also differed significantly. TD–PVR was more strongly associated with measures of poor outcomes after lung transplant. Conclusions: iFick-CO and TD-CO can be significantly different in WHO group 3 PH. In cases of discrepancy between iFick and TD-COs, TD-CO correlates better with clinical outcomes after lung transplantation. |
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| ISSN: | 2950-1334 |