Immediate outcomes of pancreatoduodenalectomy in multivisceral surgery with vascular resection
Purpose: to study the immediate outcomes of pancreaticoduodenalectomy (PD) in multivisceral surgeries (MVS) with vascular resections. Material and Methods. The study included 145 patients who underwent pancreaticoduodenalectomy with resection of the major vessels, including the superior mesenteric v...
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| Format: | Article |
| Language: | Russian |
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Russian Academy of Sciences, Tomsk National Research Medical Center
2025-05-01
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| Series: | Сибирский онкологический журнал |
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| Online Access: | https://www.siboncoj.ru/jour/article/view/3533 |
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| author | V. I. Egorov A. G. Kotelnikov Yu. I. Patyutko F. Sh. Akhmetzyanov A. N. Polyakov N. E. Kudashkin D. V. Podluzhny |
| author_facet | V. I. Egorov A. G. Kotelnikov Yu. I. Patyutko F. Sh. Akhmetzyanov A. N. Polyakov N. E. Kudashkin D. V. Podluzhny |
| author_sort | V. I. Egorov |
| collection | DOAJ |
| description | Purpose: to study the immediate outcomes of pancreaticoduodenalectomy (PD) in multivisceral surgeries (MVS) with vascular resections. Material and Methods. The study included 145 patients who underwent pancreaticoduodenalectomy with resection of the major vessels, including the superior mesenteric vein, the portal vein, and the inferior vena cava. These patients were divided into two groups. The main group included 32 patients who underwent MVS with PD, and the control group consisted of 113 patients who underwent PD. Results. There were no statistically significant differences in the immediate outcomes between two groups. Pancreatic fistula developed more often in the MVS with PD group than in the PD group (25 vs 11.5 %, p=0.055). The incidence of resected vein thrombosis in the main group was 9.4 %, in the control group was 1.8 % (p=0.07). Postoperative intra-abdominal bleeding was 6.2 % vs 8 % (p=1.0). Postoperative mortality was 6.2 % in the MVS with PD group and 8.8 % in the PD group (p=1.0). True vascular invasion was confirmed by pathomorphological examination in 20 (64.5 %) cases in the MVS with PD group and in 81 (71.7 %) cases in the PD group (p=0.44). Conclusion. Although no statistically significant differences were observed between the two groups, venous resections in multivisceral surgeries involving pancreaticoduodenalectomy demonstrated a higher incidence of pancreatodigestive anastomosis complications and a higher frequency of venous thrombosis compared to pancreaticoduodenalectomy without resection of adjacent organs, which must be taken into account when planning surgery and managing the postoperative period of this category of patients. |
| format | Article |
| id | doaj-art-a91abe9dfaf7460aae4ff30d7f7f8bf1 |
| institution | DOAJ |
| issn | 1814-4861 2312-3168 |
| language | Russian |
| publishDate | 2025-05-01 |
| publisher | Russian Academy of Sciences, Tomsk National Research Medical Center |
| record_format | Article |
| series | Сибирский онкологический журнал |
| spelling | doaj-art-a91abe9dfaf7460aae4ff30d7f7f8bf12025-08-20T03:23:19ZrusRussian Academy of Sciences, Tomsk National Research Medical CenterСибирский онкологический журнал1814-48612312-31682025-05-01242263310.21294/1814-4861-2025-24-2-26-331331Immediate outcomes of pancreatoduodenalectomy in multivisceral surgery with vascular resectionV. I. Egorov0A. G. Kotelnikov1Yu. I. Patyutko2F. Sh. Akhmetzyanov3A. N. Polyakov4N. E. Kudashkin5D. V. Podluzhny6N.N. Blokhin National Medical Research Center of Oncology оf the Ministry of Health of Russia ; Kazan State Medical University оf the Ministry of Health of Russia ; Regional Clinical Cancer Center оf the Ministry of Health of the Republic of Tatarstan named after Prof. M.Z. SigalN.N. Blokhin National Medical Research Center of Oncology оf the Ministry of Health of RussiaN.N. Blokhin National Medical Research Center of Oncology оf the Ministry of Health of RussiaKazan State Medical University оf the Ministry of Health of Russia ; Regional Clinical Cancer Center оf the Ministry of Health of the Republic of Tatarstan named after Prof. M.Z. SigalN.N. Blokhin National Medical Research Center of Oncology оf the Ministry of Health of RussiaN.N. Blokhin National Medical Research Center of Oncology оf the Ministry of Health of RussiaN.N. Blokhin National Medical Research Center of Oncology оf the Ministry of Health of RussiaPurpose: to study the immediate outcomes of pancreaticoduodenalectomy (PD) in multivisceral surgeries (MVS) with vascular resections. Material and Methods. The study included 145 patients who underwent pancreaticoduodenalectomy with resection of the major vessels, including the superior mesenteric vein, the portal vein, and the inferior vena cava. These patients were divided into two groups. The main group included 32 patients who underwent MVS with PD, and the control group consisted of 113 patients who underwent PD. Results. There were no statistically significant differences in the immediate outcomes between two groups. Pancreatic fistula developed more often in the MVS with PD group than in the PD group (25 vs 11.5 %, p=0.055). The incidence of resected vein thrombosis in the main group was 9.4 %, in the control group was 1.8 % (p=0.07). Postoperative intra-abdominal bleeding was 6.2 % vs 8 % (p=1.0). Postoperative mortality was 6.2 % in the MVS with PD group and 8.8 % in the PD group (p=1.0). True vascular invasion was confirmed by pathomorphological examination in 20 (64.5 %) cases in the MVS with PD group and in 81 (71.7 %) cases in the PD group (p=0.44). Conclusion. Although no statistically significant differences were observed between the two groups, venous resections in multivisceral surgeries involving pancreaticoduodenalectomy demonstrated a higher incidence of pancreatodigestive anastomosis complications and a higher frequency of venous thrombosis compared to pancreaticoduodenalectomy without resection of adjacent organs, which must be taken into account when planning surgery and managing the postoperative period of this category of patients.https://www.siboncoj.ru/jour/article/view/3533pancreatic cancerpancreatoduodenalectomyvascular resectionmultivisceral operationthrombosisbleeding |
| spellingShingle | V. I. Egorov A. G. Kotelnikov Yu. I. Patyutko F. Sh. Akhmetzyanov A. N. Polyakov N. E. Kudashkin D. V. Podluzhny Immediate outcomes of pancreatoduodenalectomy in multivisceral surgery with vascular resection Сибирский онкологический журнал pancreatic cancer pancreatoduodenalectomy vascular resection multivisceral operation thrombosis bleeding |
| title | Immediate outcomes of pancreatoduodenalectomy in multivisceral surgery with vascular resection |
| title_full | Immediate outcomes of pancreatoduodenalectomy in multivisceral surgery with vascular resection |
| title_fullStr | Immediate outcomes of pancreatoduodenalectomy in multivisceral surgery with vascular resection |
| title_full_unstemmed | Immediate outcomes of pancreatoduodenalectomy in multivisceral surgery with vascular resection |
| title_short | Immediate outcomes of pancreatoduodenalectomy in multivisceral surgery with vascular resection |
| title_sort | immediate outcomes of pancreatoduodenalectomy in multivisceral surgery with vascular resection |
| topic | pancreatic cancer pancreatoduodenalectomy vascular resection multivisceral operation thrombosis bleeding |
| url | https://www.siboncoj.ru/jour/article/view/3533 |
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