Laryngeal and pleural ultrasound and acoustic radiation force impulse elastography in dogs with brachycephalic obstructive airway syndrome
Abstract This study aimed to evaluate the pleural thickness, stiffness, and laryngeal stiffness in dogs clinically affected by brachycephalic obstructive airway syndrome using B-mode ultrasound and acoustic radiation force impulse elastography. Fifty-two brachycephalic pugs and French bulldogs, clin...
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Nature Portfolio
2025-06-01
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| Online Access: | https://doi.org/10.1038/s41598-025-94644-4 |
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| author | Ariadne Rein Andréia Coutinho Facin Isabella de Almeida Fabris Bruna Bressianini Lima Beatriz Gasser Luiz Paulo Nogueira Aires Ricardo Andres Ramirez Uscategui Marcus Antônio Rossi Feliciano Paola Castro Moraes |
| author_facet | Ariadne Rein Andréia Coutinho Facin Isabella de Almeida Fabris Bruna Bressianini Lima Beatriz Gasser Luiz Paulo Nogueira Aires Ricardo Andres Ramirez Uscategui Marcus Antônio Rossi Feliciano Paola Castro Moraes |
| author_sort | Ariadne Rein |
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| description | Abstract This study aimed to evaluate the pleural thickness, stiffness, and laryngeal stiffness in dogs clinically affected by brachycephalic obstructive airway syndrome using B-mode ultrasound and acoustic radiation force impulse elastography. Fifty-two brachycephalic pugs and French bulldogs, clinically classified as having brachycephalic obstructive airway syndrome (BOAS) grades 0, I, II, and III, were included, and 15 mesocephalic beagle dogs were used as the control group (CO). All animals underwent B-mode ultrasonography and subsequent elastography of the pleura and arytenoid cartilage of the larynx. Brachycephalic dogs showed greater pleural thickness than the control group dogs (p = 0.008) and a trend toward lower pleural shear wave velocity was observed in brachycephalic dogs compared to CO (p = 0.18). The larynx shear wave velocity was similar between types of skull and BOAS grades (p = 0.80). Measurements of the pleural line thickness and pleural stiffness showed moderate capacity for diagnosing brachycephalic syndrome (p = 0.01, cut-off value of > 0.82 mm and p = 0.04, cutoff value 3.29 m/s). The results suggest a secondary change in inspiratory effort at the tissue level of the pleura in dogs clinically affected by BOAS, which can be identified by B-mode ultrasound and elastography methods; however, it was not possible to diagnose changes in the arytenoid cartilage. |
| format | Article |
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| language | English |
| publishDate | 2025-06-01 |
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| spelling | doaj-art-a915207e109b4fb485a4f448b0079fe72025-08-20T02:05:13ZengNature PortfolioScientific Reports2045-23222025-06-011511910.1038/s41598-025-94644-4Laryngeal and pleural ultrasound and acoustic radiation force impulse elastography in dogs with brachycephalic obstructive airway syndromeAriadne Rein0Andréia Coutinho Facin1Isabella de Almeida Fabris2Bruna Bressianini Lima3Beatriz Gasser4Luiz Paulo Nogueira Aires5Ricardo Andres Ramirez Uscategui6Marcus Antônio Rossi Feliciano7Paola Castro Moraes8School of Agricultural and Veterinary Sciences, Department of Veterinary Clinic and Surgery, FCAV UNESPSchool of Agricultural and Veterinary Sciences, Department of Veterinary Clinic and Surgery, FCAV UNESPSchool of Agricultural and Veterinary Sciences, Department of Veterinary Clinic and Surgery, FCAV UNESPSchool of Agricultural and Veterinary Sciences, Department of Veterinary Clinic and Surgery, FCAV UNESPInstitute of Agricultural Sciences, Federal University of the Jequitinhonha and Mucuri ValleysSchool of Agricultural and Veterinary Sciences, Department of Veterinary Clinic and Surgery, FCAV UNESPUniversidad del TolimaDepartment of Veterinary Medicine, University of Sao Paulo e FZEA - USPSchool of Agricultural and Veterinary Sciences, Department of Veterinary Clinic and Surgery, FCAV UNESPAbstract This study aimed to evaluate the pleural thickness, stiffness, and laryngeal stiffness in dogs clinically affected by brachycephalic obstructive airway syndrome using B-mode ultrasound and acoustic radiation force impulse elastography. Fifty-two brachycephalic pugs and French bulldogs, clinically classified as having brachycephalic obstructive airway syndrome (BOAS) grades 0, I, II, and III, were included, and 15 mesocephalic beagle dogs were used as the control group (CO). All animals underwent B-mode ultrasonography and subsequent elastography of the pleura and arytenoid cartilage of the larynx. Brachycephalic dogs showed greater pleural thickness than the control group dogs (p = 0.008) and a trend toward lower pleural shear wave velocity was observed in brachycephalic dogs compared to CO (p = 0.18). The larynx shear wave velocity was similar between types of skull and BOAS grades (p = 0.80). Measurements of the pleural line thickness and pleural stiffness showed moderate capacity for diagnosing brachycephalic syndrome (p = 0.01, cut-off value of > 0.82 mm and p = 0.04, cutoff value 3.29 m/s). The results suggest a secondary change in inspiratory effort at the tissue level of the pleura in dogs clinically affected by BOAS, which can be identified by B-mode ultrasound and elastography methods; however, it was not possible to diagnose changes in the arytenoid cartilage.https://doi.org/10.1038/s41598-025-94644-4ArytenoidFrench bulldogHypoxiaRespiratory obstructionPleural thicknessShear wave velocity |
| spellingShingle | Ariadne Rein Andréia Coutinho Facin Isabella de Almeida Fabris Bruna Bressianini Lima Beatriz Gasser Luiz Paulo Nogueira Aires Ricardo Andres Ramirez Uscategui Marcus Antônio Rossi Feliciano Paola Castro Moraes Laryngeal and pleural ultrasound and acoustic radiation force impulse elastography in dogs with brachycephalic obstructive airway syndrome Scientific Reports Arytenoid French bulldog Hypoxia Respiratory obstruction Pleural thickness Shear wave velocity |
| title | Laryngeal and pleural ultrasound and acoustic radiation force impulse elastography in dogs with brachycephalic obstructive airway syndrome |
| title_full | Laryngeal and pleural ultrasound and acoustic radiation force impulse elastography in dogs with brachycephalic obstructive airway syndrome |
| title_fullStr | Laryngeal and pleural ultrasound and acoustic radiation force impulse elastography in dogs with brachycephalic obstructive airway syndrome |
| title_full_unstemmed | Laryngeal and pleural ultrasound and acoustic radiation force impulse elastography in dogs with brachycephalic obstructive airway syndrome |
| title_short | Laryngeal and pleural ultrasound and acoustic radiation force impulse elastography in dogs with brachycephalic obstructive airway syndrome |
| title_sort | laryngeal and pleural ultrasound and acoustic radiation force impulse elastography in dogs with brachycephalic obstructive airway syndrome |
| topic | Arytenoid French bulldog Hypoxia Respiratory obstruction Pleural thickness Shear wave velocity |
| url | https://doi.org/10.1038/s41598-025-94644-4 |
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