Prevalence and clinical implications of major and minor ANCAs in Tunisian (North African) patients with systemic lupus erythematosus

Prevalence and clinical implications of major and minor ANCAs in Tunisian (North African) patients with systemic lupus erythematosus

IntroductionAnti-neutrophil cytoplasmic antibodies (ANCAs) have been reported in systemic lupus erythematosus (SLE). Their clinical significance remains unclear especially in the African populations. This study aimed to assess the prevalence, antigenic targets, and clinical correlations of ANCAs in...

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Main Authors: Zeineb Meddeb, Houssem Abida, Dhouha Krir, Ahlem Ben Hmid, Raja Aouaidia, Cherifa Abdelkéfi, Yosra Nasri, Ines Ben Sghaier, Hayet Kebaier, Samar Samoud, Rim Goucha, Saloua B’Chir Hamzaoui, Mélika Ben Ahmed, Thara Larbi, Imen Zamali, Yousr Galai
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
systemic lupus erythematosus
ANCA
lactoferrin antibodies
disease activity
organ involvement
lupus nephritis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1657670/full
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