Recent Advances in Natural Polysaccharide-Based Hemostatic Sponges: A Review
Bleeding is a potentially life-threatening emergency that can result in severe complications or death regardless of the cause of bleeding. The development of hemostatic materials has been a long-standing concern for emergency treatment in surgery and combat. In recent years, there have been many rev...
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| Format: | Article |
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MDPI AG
2025-03-01
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| Series: | Polysaccharides |
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| Online Access: | https://www.mdpi.com/2673-4176/6/2/25 |
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| author | Yingying Guo Xuan Xie Jing Li Shun Yao |
| author_facet | Yingying Guo Xuan Xie Jing Li Shun Yao |
| author_sort | Yingying Guo |
| collection | DOAJ |
| description | Bleeding is a potentially life-threatening emergency that can result in severe complications or death regardless of the cause of bleeding. The development of hemostatic materials has been a long-standing concern for emergency treatment in surgery and combat. In recent years, there have been many reviews on hemostatic materials, but there have been few specific studies about performance requirements and development in recent years on natural polysaccharide-based hemostatic sponge as a type of hemostatic excipient. Currently, natural polysaccharide hemostatic sponge has attracted wide attention due to the enhancement or interaction of various hemostatic mechanisms. These polysaccharide sponges show a high hemostatic effect. In this paper, the application history of natural polysaccharides (chitosan, hyaluronic acid, alginate, cellulose, starch, etc.) as a new generation of hemostatic sponge materials in recent years is reviewed. The design principles and new achievements in polysaccharide-based hemostatic sponge are introduced. Finally, we summarize the advantages and disadvantages of polysaccharide hemostatic sponge and prospect the development opportunities and challenges of this material. |
| format | Article |
| id | doaj-art-a90bf35de14c4db5b9d7fdc18911d31d |
| institution | DOAJ |
| issn | 2673-4176 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polysaccharides |
| spelling | doaj-art-a90bf35de14c4db5b9d7fdc18911d31d2025-08-20T03:16:36ZengMDPI AGPolysaccharides2673-41762025-03-01622510.3390/polysaccharides6020025Recent Advances in Natural Polysaccharide-Based Hemostatic Sponges: A ReviewYingying Guo0Xuan Xie1Jing Li2Shun Yao3School of Pharmacy, Chengdu Medical College, Chengdu 610500, ChinaSchool of Pharmacy, Chengdu Medical College, Chengdu 610500, ChinaThe College of Life Sciences, Sichuan University, Chengdu 610064, ChinaSchool of Chemical Engineering, Sichuan University, Chengdu 610065, ChinaBleeding is a potentially life-threatening emergency that can result in severe complications or death regardless of the cause of bleeding. The development of hemostatic materials has been a long-standing concern for emergency treatment in surgery and combat. In recent years, there have been many reviews on hemostatic materials, but there have been few specific studies about performance requirements and development in recent years on natural polysaccharide-based hemostatic sponge as a type of hemostatic excipient. Currently, natural polysaccharide hemostatic sponge has attracted wide attention due to the enhancement or interaction of various hemostatic mechanisms. These polysaccharide sponges show a high hemostatic effect. In this paper, the application history of natural polysaccharides (chitosan, hyaluronic acid, alginate, cellulose, starch, etc.) as a new generation of hemostatic sponge materials in recent years is reviewed. The design principles and new achievements in polysaccharide-based hemostatic sponge are introduced. Finally, we summarize the advantages and disadvantages of polysaccharide hemostatic sponge and prospect the development opportunities and challenges of this material.https://www.mdpi.com/2673-4176/6/2/25natural polysaccharideshemostatic spongedesign principleshemostatic mechanism |
| spellingShingle | Yingying Guo Xuan Xie Jing Li Shun Yao Recent Advances in Natural Polysaccharide-Based Hemostatic Sponges: A Review Polysaccharides natural polysaccharides hemostatic sponge design principles hemostatic mechanism |
| title | Recent Advances in Natural Polysaccharide-Based Hemostatic Sponges: A Review |
| title_full | Recent Advances in Natural Polysaccharide-Based Hemostatic Sponges: A Review |
| title_fullStr | Recent Advances in Natural Polysaccharide-Based Hemostatic Sponges: A Review |
| title_full_unstemmed | Recent Advances in Natural Polysaccharide-Based Hemostatic Sponges: A Review |
| title_short | Recent Advances in Natural Polysaccharide-Based Hemostatic Sponges: A Review |
| title_sort | recent advances in natural polysaccharide based hemostatic sponges a review |
| topic | natural polysaccharides hemostatic sponge design principles hemostatic mechanism |
| url | https://www.mdpi.com/2673-4176/6/2/25 |
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