Molecular Mechanism of Targeted Inhibition of Pancreatic Lipase and Cholesterol Esterase by Hempseed Peptides

Molecular Mechanism of Targeted Inhibition of Pancreatic Lipase and Cholesterol Esterase by Hempseed Peptides

In this study, we systematically investigated the regulatory effects of two hempseed peptides (APAM and RLPA) on pancreatic lipase (PL) and cholesterol esterase (CE) activities and the molecular binding mechanism using enzyme kinetics, synergistic inhibition, fluorescence spectroscopy, isothermal ti...

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Bibliographic Details
Main Author: YIN Hao, ZHU Jiangxiong, ZHAO Haiyun, ZHONG Yu, WANG Danfeng, DENG Yun
Format: Article
Language:English
Published: China Food Publishing Company 2025-01-01
Series:Shipin Kexue
Subjects:
lipid-digesting enzymes; inhibition mechanism; fluorescence spectroscopy; isothermal titration calorimetry; molecular modeling
Online Access:https://www.spkx.net.cn/fileup/1002-6630/PDF/2025-46-2-005.pdf
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