Alpha-1 antitrypsin promotes re-epithelialization by regulating inflammation and migration

Alpha-1 antitrypsin promotes re-epithelialization by regulating inflammation and migration

PurposeRegulation of inflammation and re-epithelialization are critical for efficient wound healing. This study explores the role of human α1-antitrypsin (hAAT), an immunomodulatory protein, in modulating inflammation and promoting re-epithelialization across various epithelial cell types.MethodsIn-...

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Bibliographic Details
Main Authors: Idan Farber, Muhammad Wated, Ronen Schuster, Lihie Sheffer, Yuval Anav, Navit Ogen-Shtern, Alexandra Tsitrina, Diya Tacruri, Anna Bunin, Noah Benjamin Nagar, Maayan Hagbi Bal, Tomer Eliyahu, Dor Halpern, Boris Knyazer, Samuel Cohen, Sabri El-Saied, Eli C. Lewis, Eldad Silberstein, Erez Tsumi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
adhesion molecules
corneal abrasion
desmosomes
gene expression
hemidesmosomes
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1586039/full
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