Epigenetic dysregulation-induced metabolic reprogramming fuels tumor progression in bladder cancer

Epigenetic dysregulation-induced metabolic reprogramming fuels tumor progression in bladder cancer

BackgroundBladder cancer remains a significant global health challenge with a high mortality rate despite advancements in treatment modalities. Metabolic alterations serve as crucial contributors to cancer progression, particularly influencing tumor aggressiveness and patient outcomes. Therefore, th...

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Bibliographic Details
Main Authors: Jian Zhang, Xiaosong Fan, Xu Xu, Yichao Han, Weixing Yu, Bicheng Yang, Yanling Chen, Shaolin Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
bladder cancer
metabolic reprogramming
tumor aggressiveness
inflammation
DNA methylation
USF2
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1602700/full
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