Deciphering antigen-specific T cell navigation tactics and cancer immune evasion in co-cultures

Deciphering antigen-specific T cell navigation tactics and cancer immune evasion in co-cultures

Abstract Insufficient infiltration of cytotoxic T cells into solid tumors remains a critical obstacle in cancer immunotherapy. Despite extensive efforts to comprehend the mechanisms governing this limited infiltration, few studies have focused on the evolution of T cell motility behavior after co-cu...

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Bibliographic Details
Main Authors: Xinyue Li, Taoli Jin, Lisha Wang, Senbin Wu, Yerong Liu, Ming Li, Weijing Han, Xuefei Li
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08568-w
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