Safety and efficacy of praziquantel in pregnant women infected with Schistosoma haematobium in Lambaréné, Gabon – Clinical results from the randomized, single-blinded, controlled freeBILy-Gabon trial

Safety and efficacy of praziquantel in pregnant women infected with Schistosoma haematobium in Lambaréné, Gabon – Clinical results from the randomized, single-blinded, controlled freeBILy-Gabon trial

Objectives: Despite evidence of praziquantel's (PZQ) safety for treating schistosomiasis in pregnancy, many countries withhold treatment. Only two randomized controlled trials have investigated PZQ in pregnancy, none involving Schistosoma haematobium. Methods: Pregnant women during the second t...

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Main Authors: Jacob Gerstenberg, Yabo J. Honkpehedji, Jean-Claude Dejon-Agobe, Saidou Mahmoudou, Mario Recker, Romuald Beh Mba, Moustapha Nzamba Maloum, Romeo Laclong Lontchi, Paul A. Nguema Moure, Brice Meulah, Jeannot F. Zinsou, Jean-Ronald Edoa, Bayode R. Adegbite, Michael Ramharter, Bertrand Lell, Selidji T. Agnandji, Peter G. Kremsner, Paul L.A.M. Corstjens, Pytsje T. Hoekstra, Govert J. van Dam, Andrea Kreidenweiss, Ayola A. Adegnika
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:International Journal of Infectious Diseases
Subjects:
Pregnancy
Schistosomiasis
S. haematobium
Praziquantel
Safety
Efficacy
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971224003242
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