Giant Parathyroid Tumor: Parathyroid Adenoma versus Parathyroid Carcinoma

Parathyroid adenoma is the most common cause of primary hyperparathyroidism (PHPT). We present the preoperative detection of a giant parathyroid adenoma (GPA) using (99mTc)-sestamibi parathyroid scintigraphy in a patient presenting with severely elevated parathyroid hormone, hypercalcemia, hypophosp...

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Main Authors: Farid Gossili, Allan Carlé, Trine B. Andersen, Helle D Zacho
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2022/7712097
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author Farid Gossili
Allan Carlé
Trine B. Andersen
Helle D Zacho
author_facet Farid Gossili
Allan Carlé
Trine B. Andersen
Helle D Zacho
author_sort Farid Gossili
collection DOAJ
description Parathyroid adenoma is the most common cause of primary hyperparathyroidism (PHPT). We present the preoperative detection of a giant parathyroid adenoma (GPA) using (99mTc)-sestamibi parathyroid scintigraphy in a patient presenting with severely elevated parathyroid hormone, hypercalcemia, hypophosphatemia, and vitamin D insufficiency. The patient complained of cerebral symptoms and intermittent abdominal discomfort without constipation. After surgical removal of the hyperactive parathyroid gland and D vitamin supplementation, all blood tests were normalized. The clinical and paraclinical characteristics of GPA may raise the suspicion of parathyroid carcinoma, but not absolutely in this case.
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institution Kabale University
issn 2090-651X
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publishDate 2022-01-01
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series Case Reports in Endocrinology
spelling doaj-art-a8a0316128a54b18b2a2d2844cc971622025-08-20T03:39:09ZengWileyCase Reports in Endocrinology2090-651X2022-01-01202210.1155/2022/7712097Giant Parathyroid Tumor: Parathyroid Adenoma versus Parathyroid CarcinomaFarid Gossili0Allan Carlé1Trine B. Andersen2Helle D Zacho3Department of Nuclear MedicineDepartment of EndocrinologyDepartment of Nuclear MedicineDepartment of Nuclear MedicineParathyroid adenoma is the most common cause of primary hyperparathyroidism (PHPT). We present the preoperative detection of a giant parathyroid adenoma (GPA) using (99mTc)-sestamibi parathyroid scintigraphy in a patient presenting with severely elevated parathyroid hormone, hypercalcemia, hypophosphatemia, and vitamin D insufficiency. The patient complained of cerebral symptoms and intermittent abdominal discomfort without constipation. After surgical removal of the hyperactive parathyroid gland and D vitamin supplementation, all blood tests were normalized. The clinical and paraclinical characteristics of GPA may raise the suspicion of parathyroid carcinoma, but not absolutely in this case.http://dx.doi.org/10.1155/2022/7712097
spellingShingle Farid Gossili
Allan Carlé
Trine B. Andersen
Helle D Zacho
Giant Parathyroid Tumor: Parathyroid Adenoma versus Parathyroid Carcinoma
Case Reports in Endocrinology
title Giant Parathyroid Tumor: Parathyroid Adenoma versus Parathyroid Carcinoma
title_full Giant Parathyroid Tumor: Parathyroid Adenoma versus Parathyroid Carcinoma
title_fullStr Giant Parathyroid Tumor: Parathyroid Adenoma versus Parathyroid Carcinoma
title_full_unstemmed Giant Parathyroid Tumor: Parathyroid Adenoma versus Parathyroid Carcinoma
title_short Giant Parathyroid Tumor: Parathyroid Adenoma versus Parathyroid Carcinoma
title_sort giant parathyroid tumor parathyroid adenoma versus parathyroid carcinoma
url http://dx.doi.org/10.1155/2022/7712097
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AT helledzacho giantparathyroidtumorparathyroidadenomaversusparathyroidcarcinoma