Giant Parathyroid Tumor: Parathyroid Adenoma versus Parathyroid Carcinoma

Parathyroid adenoma is the most common cause of primary hyperparathyroidism (PHPT). We present the preoperative detection of a giant parathyroid adenoma (GPA) using (99mTc)-sestamibi parathyroid scintigraphy in a patient presenting with severely elevated parathyroid hormone, hypercalcemia, hypophosp...

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Bibliographic Details
Main Authors: Farid Gossili, Allan Carlé, Trine B. Andersen, Helle D Zacho
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2022/7712097
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Summary:Parathyroid adenoma is the most common cause of primary hyperparathyroidism (PHPT). We present the preoperative detection of a giant parathyroid adenoma (GPA) using (99mTc)-sestamibi parathyroid scintigraphy in a patient presenting with severely elevated parathyroid hormone, hypercalcemia, hypophosphatemia, and vitamin D insufficiency. The patient complained of cerebral symptoms and intermittent abdominal discomfort without constipation. After surgical removal of the hyperactive parathyroid gland and D vitamin supplementation, all blood tests were normalized. The clinical and paraclinical characteristics of GPA may raise the suspicion of parathyroid carcinoma, but not absolutely in this case.
ISSN:2090-651X