Relationship Between Child Turcotte Pugh (CTP) Score and Esophageal Varices (EV) Among Sudanese Cirrhotic Patients in Wad Madani Teaching Hospital, 2024: A Cross‐Sectional Study
ABSTRACT Background Esophageal varices (EV) are a fatal complication of cirrhosis. The guidelines suggest that esophageal varices should be diagnosed before bleeding in all patients. In patients with cirrhosis, the Child Turcotte Pugh (CTP) class has been used as a prognostic tool for variceal bleed...
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2025-06-01
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| Online Access: | https://doi.org/10.1002/hsr2.70918 |
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| author | Eltype Elsiddig Alaaeldeen Alhassan Osman Amir Moawia Elbalal |
| author_facet | Eltype Elsiddig Alaaeldeen Alhassan Osman Amir Moawia Elbalal |
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| description | ABSTRACT Background Esophageal varices (EV) are a fatal complication of cirrhosis. The guidelines suggest that esophageal varices should be diagnosed before bleeding in all patients. In patients with cirrhosis, the Child Turcotte Pugh (CTP) class has been used as a prognostic tool for variceal bleeding. Aim To study the correlation between CTP score and EV among cirrhotic patients. Methods A descriptive cross‐sectional study enrolled 67 cirrhotic patients who attended Wad Madani Teaching Hospital during the period from November 2020 to November 2021. Data regarding demographics, clinical history, presentations, ultrasound findings and laboratory investigations were collected. CTP and model for end‐stage liver disease (MELD) scores were calculated for all patients. Upper gastrointestinal (UGI) endoscopy was performed and EV grades were correlated with MELD and CTP. Results Among 67 patients, 46 (69%) were males and 21 (31%) were females, and their mean age was 52 ± 13 years. Most of the cases were CTP‐C (49%) and had MELD score from 20 to 29 (41.8%). UGI endoscopy showed Grade‐III EV in the majority of the patients (46.3%). CTP‐C and MELD scores ≥ 40 were significantly associated with advanced grades of EV (Grades III and IV) (p‐value < 0.0001). Also, hyperbilirubinemia, hypoalbuminemia and high INR levels were significantly associated with Grades III and IV EV (p‐value < 0.0001). Conclusion The cirrhotic patients with higher MELD and CTP scores had advanced grades of EV. The study recommends that patients with Child Pugh's score B and C should have close EGD intervals due to the probability of having advance EV. |
| format | Article |
| id | doaj-art-a89e269b28704dcf9504b245bd014c75 |
| institution | Kabale University |
| issn | 2398-8835 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Wiley |
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| spelling | doaj-art-a89e269b28704dcf9504b245bd014c752025-08-20T03:24:07ZengWileyHealth Science Reports2398-88352025-06-0186n/an/a10.1002/hsr2.70918Relationship Between Child Turcotte Pugh (CTP) Score and Esophageal Varices (EV) Among Sudanese Cirrhotic Patients in Wad Madani Teaching Hospital, 2024: A Cross‐Sectional StudyEltype Elsiddig0Alaaeldeen Alhassan1Osman Amir2Moawia ElbalalAl Hasahisa Teaching Hospital Al Hasahisa SudanUniversity of Gezira Wad Madani SudanDepartment of Hematology, Faculty of Medical Laboratory Sciences Karary University Omdurman SudanABSTRACT Background Esophageal varices (EV) are a fatal complication of cirrhosis. The guidelines suggest that esophageal varices should be diagnosed before bleeding in all patients. In patients with cirrhosis, the Child Turcotte Pugh (CTP) class has been used as a prognostic tool for variceal bleeding. Aim To study the correlation between CTP score and EV among cirrhotic patients. Methods A descriptive cross‐sectional study enrolled 67 cirrhotic patients who attended Wad Madani Teaching Hospital during the period from November 2020 to November 2021. Data regarding demographics, clinical history, presentations, ultrasound findings and laboratory investigations were collected. CTP and model for end‐stage liver disease (MELD) scores were calculated for all patients. Upper gastrointestinal (UGI) endoscopy was performed and EV grades were correlated with MELD and CTP. Results Among 67 patients, 46 (69%) were males and 21 (31%) were females, and their mean age was 52 ± 13 years. Most of the cases were CTP‐C (49%) and had MELD score from 20 to 29 (41.8%). UGI endoscopy showed Grade‐III EV in the majority of the patients (46.3%). CTP‐C and MELD scores ≥ 40 were significantly associated with advanced grades of EV (Grades III and IV) (p‐value < 0.0001). Also, hyperbilirubinemia, hypoalbuminemia and high INR levels were significantly associated with Grades III and IV EV (p‐value < 0.0001). Conclusion The cirrhotic patients with higher MELD and CTP scores had advanced grades of EV. The study recommends that patients with Child Pugh's score B and C should have close EGD intervals due to the probability of having advance EV.https://doi.org/10.1002/hsr2.70918Child Pugh scorecirrhosisesophageal varicesSudanese |
| spellingShingle | Eltype Elsiddig Alaaeldeen Alhassan Osman Amir Moawia Elbalal Relationship Between Child Turcotte Pugh (CTP) Score and Esophageal Varices (EV) Among Sudanese Cirrhotic Patients in Wad Madani Teaching Hospital, 2024: A Cross‐Sectional Study Health Science Reports Child Pugh score cirrhosis esophageal varices Sudanese |
| title | Relationship Between Child Turcotte Pugh (CTP) Score and Esophageal Varices (EV) Among Sudanese Cirrhotic Patients in Wad Madani Teaching Hospital, 2024: A Cross‐Sectional Study |
| title_full | Relationship Between Child Turcotte Pugh (CTP) Score and Esophageal Varices (EV) Among Sudanese Cirrhotic Patients in Wad Madani Teaching Hospital, 2024: A Cross‐Sectional Study |
| title_fullStr | Relationship Between Child Turcotte Pugh (CTP) Score and Esophageal Varices (EV) Among Sudanese Cirrhotic Patients in Wad Madani Teaching Hospital, 2024: A Cross‐Sectional Study |
| title_full_unstemmed | Relationship Between Child Turcotte Pugh (CTP) Score and Esophageal Varices (EV) Among Sudanese Cirrhotic Patients in Wad Madani Teaching Hospital, 2024: A Cross‐Sectional Study |
| title_short | Relationship Between Child Turcotte Pugh (CTP) Score and Esophageal Varices (EV) Among Sudanese Cirrhotic Patients in Wad Madani Teaching Hospital, 2024: A Cross‐Sectional Study |
| title_sort | relationship between child turcotte pugh ctp score and esophageal varices ev among sudanese cirrhotic patients in wad madani teaching hospital 2024 a cross sectional study |
| topic | Child Pugh score cirrhosis esophageal varices Sudanese |
| url | https://doi.org/10.1002/hsr2.70918 |
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