Potential of CLSPN as a therapeutic target in melanoma: a key player in melanoma progression and tumor microenvironment

Potential of CLSPN as a therapeutic target in melanoma: a key player in melanoma progression and tumor microenvironment

Abstract Background Melanoma is a highly aggressive form of skin cancer. Despite significant advances in targeted therapies and immunotherapeutic approaches, some patients still have poor response rates, making a deeper understanding of melanoma pathogenesis essential. Methods The expression of Clas...

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Bibliographic Details
Main Authors: Yongyi Xie, Ruoqi Wang, Mingyuan Xu, Jiashe Chen, Wei Tan, Yanbin Chen, Yun Bai, Nanhui Wu, Fei Wu, Xiaoxiang Xu, Xin Ma, Yeqiang Liu
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Journal of Translational Medicine
Subjects:
CLSPN
SKCM
TAMs
Tumor immunological microenvironment
Online Access:https://doi.org/10.1186/s12967-025-06455-w
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