Improving the Activity and Selectivity of a Scorpion-Derived Peptide, A3a, against Acinetobacter baumannii through Rational Design

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Main Authors: Dalton S. Möller, Mandelie van der Walt, Carel Oosthuizen, Miruna Serian, June C. Serem, Christian D. Lorenz, A. James Mason, Megan J. Bester, Anabella R. M. Gaspar
Format: Article
Language:English
Published: American Chemical Society 2025-01-01
Series:ACS Omega
Online Access:https://doi.org/10.1021/acsomega.4c09593
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author Dalton S. Möller
Mandelie van der Walt
Carel Oosthuizen
Miruna Serian
June C. Serem
Christian D. Lorenz
A. James Mason
Megan J. Bester
Anabella R. M. Gaspar
author_facet Dalton S. Möller
Mandelie van der Walt
Carel Oosthuizen
Miruna Serian
June C. Serem
Christian D. Lorenz
A. James Mason
Megan J. Bester
Anabella R. M. Gaspar
author_sort Dalton S. Möller
collection DOAJ
format Article
id doaj-art-a897b54a4a0444e1aa26aa71e12ed7cf
institution Kabale University
issn 2470-1343
language English
publishDate 2025-01-01
publisher American Chemical Society
record_format Article
series ACS Omega
spelling doaj-art-a897b54a4a0444e1aa26aa71e12ed7cf2025-02-11T09:08:48ZengAmerican Chemical SocietyACS Omega2470-13432025-01-011054699471010.1021/acsomega.4c09593Improving the Activity and Selectivity of a Scorpion-Derived Peptide, A3a, against Acinetobacter baumannii through Rational DesignDalton S. Möller0Mandelie van der Walt1Carel Oosthuizen2Miruna Serian3June C. Serem4Christian D. Lorenz5A. James Mason6Megan J. Bester7Anabella R. M. Gaspar8Department of Biochemistry, Genetics and Microbiology, Faculty of Natural and Agricultural Sciences, University of Pretoria, Pretoria, South AfricaDepartment of Biochemistry, Genetics and Microbiology, Faculty of Natural and Agricultural Sciences, University of Pretoria, Pretoria, South AfricaDrug Discovery and Development Centre (H3D), University of Cape Town, Rondebosch, South AfricaDepartment of Physics, Faculty of Natural, Mathematical and Engineering Sciences, King’s College London, London, U.K.Department of Anatomy, Faculty of Health Sciences, University of Pretoria, Pretoria, South AfricaDepartment of Engineering, Faculty of Natural, Mathematical and Engineering Sciences, King’s College London, London, U.K.Institute of Pharmaceutical Science, School of Cancer & Pharmaceutical Science, Faculty of Life Sciences & Medicine, King’s College London, London, U.K.Department of Anatomy, Faculty of Health Sciences, University of Pretoria, Pretoria, South AfricaDepartment of Biochemistry, Genetics and Microbiology, Faculty of Natural and Agricultural Sciences, University of Pretoria, Pretoria, South Africahttps://doi.org/10.1021/acsomega.4c09593
spellingShingle Dalton S. Möller
Mandelie van der Walt
Carel Oosthuizen
Miruna Serian
June C. Serem
Christian D. Lorenz
A. James Mason
Megan J. Bester
Anabella R. M. Gaspar
Improving the Activity and Selectivity of a Scorpion-Derived Peptide, A3a, against Acinetobacter baumannii through Rational Design
ACS Omega
title Improving the Activity and Selectivity of a Scorpion-Derived Peptide, A3a, against Acinetobacter baumannii through Rational Design
title_full Improving the Activity and Selectivity of a Scorpion-Derived Peptide, A3a, against Acinetobacter baumannii through Rational Design
title_fullStr Improving the Activity and Selectivity of a Scorpion-Derived Peptide, A3a, against Acinetobacter baumannii through Rational Design
title_full_unstemmed Improving the Activity and Selectivity of a Scorpion-Derived Peptide, A3a, against Acinetobacter baumannii through Rational Design
title_short Improving the Activity and Selectivity of a Scorpion-Derived Peptide, A3a, against Acinetobacter baumannii through Rational Design
title_sort improving the activity and selectivity of a scorpion derived peptide a3a against acinetobacter baumannii through rational design
url https://doi.org/10.1021/acsomega.4c09593
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