GADOLINIUM RETENTION IN HUMANS: SURVEY OF RADIOLOGISTS AND IMPACT ON DAILY PRACTICE

Objective: We sought to assess the 1) awareness and impact of emerging gadolinium retention data on preferences of radiologists in their practice, and 2) factors that influence the attitudes about gadolinium use and risk. This study also documents various specifics of radiology practice in Turkey. M...

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Main Authors: Mehmet Emin Adın, David M. Yousem
Format: Article
Language:English
Published: Istanbul University Press 2021-07-01
Series:İstanbul Tıp Fakültesi Dergisi
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Online Access:https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/2EDEA058D9AA47298A6FB244D6201E45
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author Mehmet Emin Adın
David M. Yousem
author_facet Mehmet Emin Adın
David M. Yousem
author_sort Mehmet Emin Adın
collection DOAJ
description Objective: We sought to assess the 1) awareness and impact of emerging gadolinium retention data on preferences of radiologists in their practice, and 2) factors that influence the attitudes about gadolinium use and risk. This study also documents various specifics of radiology practice in Turkey. Methods: A twenty-one question survey was directed to radiologists who were at least one year from completion of residency and/or fellowship training. A survey link was emailed to the members of the Turkish Society of Radiology and was active for four weeks. The results were statistically analyzed. Results: Three hundred and thirty-five radiologists completed the survey. At the time of this survey, 89% of respondents were aware of gadolinium retention in the brain. Forty-five percent of respondents said they decreased the amount of gadolinium administered and/or frequency of gadolinium-enhanced scans since the emergence of the gadolinium retention data. Eightyeight percent of radiologists, who were aware of the molecular classification of different gadolinium agents, used a macrocyclic agent. Thirty-nine percent (n=130) had switched to a macrocyclic agent from a linear agent within the previous three years. Radiologists’ attitudes toward gadolinium retention were significantly associated with their background factors such as experience in radiology, subspecialty training, and daily work definition, amongst others. Observence of hyperintense dentate nuclei due to gadolinium retention was uncommon in daily practice. Conclusions: Gadolinium retention publications have affected the practice of contrast enhanced Magnetic resonance imaging (MRI) scans, mostly in the form of switching to a macrocyclic gadolinium agent and decreasing utilization of gadolinium in general for some indications. These changes varied among radiologists by background factors.
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spelling doaj-art-a88f09079a8d4f0da3258a50e102d5be2025-08-20T01:50:21ZengIstanbul University Pressİstanbul Tıp Fakültesi Dergisi1305-64412021-07-0184333134110.26650/IUITFD.2021.874672123456GADOLINIUM RETENTION IN HUMANS: SURVEY OF RADIOLOGISTS AND IMPACT ON DAILY PRACTICEMehmet Emin Adın0https://orcid.org/0000-0002-0070-9998David M. Yousem1https://orcid.org/0000-0002-1222-6643Yale School of Medicine, Connecticut, United-StatesJohns Hopkins University School of Medicine, Maryland, United-StatesObjective: We sought to assess the 1) awareness and impact of emerging gadolinium retention data on preferences of radiologists in their practice, and 2) factors that influence the attitudes about gadolinium use and risk. This study also documents various specifics of radiology practice in Turkey. Methods: A twenty-one question survey was directed to radiologists who were at least one year from completion of residency and/or fellowship training. A survey link was emailed to the members of the Turkish Society of Radiology and was active for four weeks. The results were statistically analyzed. Results: Three hundred and thirty-five radiologists completed the survey. At the time of this survey, 89% of respondents were aware of gadolinium retention in the brain. Forty-five percent of respondents said they decreased the amount of gadolinium administered and/or frequency of gadolinium-enhanced scans since the emergence of the gadolinium retention data. Eightyeight percent of radiologists, who were aware of the molecular classification of different gadolinium agents, used a macrocyclic agent. Thirty-nine percent (n=130) had switched to a macrocyclic agent from a linear agent within the previous three years. Radiologists’ attitudes toward gadolinium retention were significantly associated with their background factors such as experience in radiology, subspecialty training, and daily work definition, amongst others. Observence of hyperintense dentate nuclei due to gadolinium retention was uncommon in daily practice. Conclusions: Gadolinium retention publications have affected the practice of contrast enhanced Magnetic resonance imaging (MRI) scans, mostly in the form of switching to a macrocyclic gadolinium agent and decreasing utilization of gadolinium in general for some indications. These changes varied among radiologists by background factors.https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/2EDEA058D9AA47298A6FB244D6201E45gadoliniummagnetic resonance imagingsurveys and questionnairesradiologistscerebellar nuclei
spellingShingle Mehmet Emin Adın
David M. Yousem
GADOLINIUM RETENTION IN HUMANS: SURVEY OF RADIOLOGISTS AND IMPACT ON DAILY PRACTICE
İstanbul Tıp Fakültesi Dergisi
gadolinium
magnetic resonance imaging
surveys and questionnaires
radiologists
cerebellar nuclei
title GADOLINIUM RETENTION IN HUMANS: SURVEY OF RADIOLOGISTS AND IMPACT ON DAILY PRACTICE
title_full GADOLINIUM RETENTION IN HUMANS: SURVEY OF RADIOLOGISTS AND IMPACT ON DAILY PRACTICE
title_fullStr GADOLINIUM RETENTION IN HUMANS: SURVEY OF RADIOLOGISTS AND IMPACT ON DAILY PRACTICE
title_full_unstemmed GADOLINIUM RETENTION IN HUMANS: SURVEY OF RADIOLOGISTS AND IMPACT ON DAILY PRACTICE
title_short GADOLINIUM RETENTION IN HUMANS: SURVEY OF RADIOLOGISTS AND IMPACT ON DAILY PRACTICE
title_sort gadolinium retention in humans survey of radiologists and impact on daily practice
topic gadolinium
magnetic resonance imaging
surveys and questionnaires
radiologists
cerebellar nuclei
url https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/2EDEA058D9AA47298A6FB244D6201E45
work_keys_str_mv AT mehmeteminadın gadoliniumretentioninhumanssurveyofradiologistsandimpactondailypractice
AT davidmyousem gadoliniumretentioninhumanssurveyofradiologistsandimpactondailypractice