Нelicobacter pylori as etiological factor of acute pancreatitis and marker of its purulent-septic complications development
Objective. Studying of role of Нelicobacter pylori as etiological factor of acute pancreatitis and marker of development of its purulent-septic complications. Маterials and methods. Screening investigation was performed in all 124 patients, suffering acute pancreatitis and admitted to hospital; t...
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Liga-Inform ltd.
2020-09-01
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| Series: | Клінічна хірургія |
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| Online Access: | https://hirurgiya.com.ua/index.php/journal/article/view/841 |
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| author | І. V. Коlosovych І. V. Hanol К. О. Lebedieva |
| author_facet | І. V. Коlosovych І. V. Hanol К. О. Lebedieva |
| author_sort | І. V. Коlosovych |
| collection | DOAJ |
| description | Objective. Studying of role of Нelicobacter pylori as etiological factor of acute pancreatitis and marker of development of its purulent-septic complications.
Маterials and methods. Screening investigation was performed in all 124 patients, suffering acute pancreatitis and admitted to hospital; then a screening investigation of Нelicobacter pylori in feces and the blood serological investigation was conducted. In 39 (31.5%) patients bacteriological investigation of biological material for revealing of Нelicobacter pylori was conducted. The patients were distributed into two groups: the main - 66 patients with severe and with a middle severity course of acute pancreatitis and a control one - 58 patients with light course of acute pancreatitis.
Results. Positive results of fecal express-test were obtained in 105 (84.7%) patients. In accordance to the blood serological investigations results in 24 h from the admittance to hospital moment in a control group a positive result was obtained in 8 (13.8%) patients, and in the main - in 23 (34.8%); while in 7 days - in 9 (15.5%) and 42 (63.6%) patients, accordingly. Аntibiotics, which are applied for therapy in purulent-septic complications of acute pancreatitis, guarantee the efficacy of eradication of Нelicobacter pylori in 94.9% patients.
Conclusion. The enhancement of quantity of the blood positive serological investigations by 28.8% (р < 0.001) in patients of the main group in 7 days from the admittance to the hospital date trusts, that Нelicobacter pylori constitutes not the only one etiological factor in acute pancreatitis, but a possible marker of development of its purulent-septic complications as well. |
| format | Article |
| id | doaj-art-a88e48ed8f264c928ca81a8b0bf34550 |
| institution | DOAJ |
| issn | 0023-2130 2522-1396 |
| language | English |
| publishDate | 2020-09-01 |
| publisher | Liga-Inform ltd. |
| record_format | Article |
| series | Клінічна хірургія |
| spelling | doaj-art-a88e48ed8f264c928ca81a8b0bf345502025-08-20T02:51:49ZengLiga-Inform ltd.Клінічна хірургія0023-21302522-13962020-09-01877-8151910.26779/2522-1396.2020.7-8.15841Нelicobacter pylori as etiological factor of acute pancreatitis and marker of its purulent-septic complications developmentІ. V. Коlosovych0І. V. Hanol1К. О. Lebedieva2Bogomolets National Medical University, KyivBogomolets National Medical University, KyivBogomolets National Medical University, KyivObjective. Studying of role of Нelicobacter pylori as etiological factor of acute pancreatitis and marker of development of its purulent-septic complications. Маterials and methods. Screening investigation was performed in all 124 patients, suffering acute pancreatitis and admitted to hospital; then a screening investigation of Нelicobacter pylori in feces and the blood serological investigation was conducted. In 39 (31.5%) patients bacteriological investigation of biological material for revealing of Нelicobacter pylori was conducted. The patients were distributed into two groups: the main - 66 patients with severe and with a middle severity course of acute pancreatitis and a control one - 58 patients with light course of acute pancreatitis. Results. Positive results of fecal express-test were obtained in 105 (84.7%) patients. In accordance to the blood serological investigations results in 24 h from the admittance to hospital moment in a control group a positive result was obtained in 8 (13.8%) patients, and in the main - in 23 (34.8%); while in 7 days - in 9 (15.5%) and 42 (63.6%) patients, accordingly. Аntibiotics, which are applied for therapy in purulent-septic complications of acute pancreatitis, guarantee the efficacy of eradication of Нelicobacter pylori in 94.9% patients. Conclusion. The enhancement of quantity of the blood positive serological investigations by 28.8% (р < 0.001) in patients of the main group in 7 days from the admittance to the hospital date trusts, that Нelicobacter pylori constitutes not the only one etiological factor in acute pancreatitis, but a possible marker of development of its purulent-septic complications as well.https://hirurgiya.com.ua/index.php/journal/article/view/841helicobacter pylori; acute pancreatitis; purulent-septic complications. |
| spellingShingle | І. V. Коlosovych І. V. Hanol К. О. Lebedieva Нelicobacter pylori as etiological factor of acute pancreatitis and marker of its purulent-septic complications development Клінічна хірургія helicobacter pylori; acute pancreatitis; purulent-septic complications. |
| title | Нelicobacter pylori as etiological factor of acute pancreatitis and marker of its purulent-septic complications development |
| title_full | Нelicobacter pylori as etiological factor of acute pancreatitis and marker of its purulent-septic complications development |
| title_fullStr | Нelicobacter pylori as etiological factor of acute pancreatitis and marker of its purulent-septic complications development |
| title_full_unstemmed | Нelicobacter pylori as etiological factor of acute pancreatitis and marker of its purulent-septic complications development |
| title_short | Нelicobacter pylori as etiological factor of acute pancreatitis and marker of its purulent-septic complications development |
| title_sort | нelicobacter pylori as etiological factor of acute pancreatitis and marker of its purulent septic complications development |
| topic | helicobacter pylori; acute pancreatitis; purulent-septic complications. |
| url | https://hirurgiya.com.ua/index.php/journal/article/view/841 |
| work_keys_str_mv | AT ívkolosovych nelicobacterpyloriasetiologicalfactorofacutepancreatitisandmarkerofitspurulentsepticcomplicationsdevelopment AT ívhanol nelicobacterpyloriasetiologicalfactorofacutepancreatitisandmarkerofitspurulentsepticcomplicationsdevelopment AT kolebedieva nelicobacterpyloriasetiologicalfactorofacutepancreatitisandmarkerofitspurulentsepticcomplicationsdevelopment |