Tailoring oral targeted therapies dosage in lung cancer: A systematic review of pharmacokinetics studies on renal and hepatic impairment.

Tailoring oral targeted therapies dosage in lung cancer: A systematic review of pharmacokinetics studies on renal and hepatic impairment.

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<h4>Background</h4>Lung cancer is the leading cause of cancer-related deaths worldwide, and stage IV lung cancer is frequently managed with targeted therapy. Renal and hepatic impairment frequently coexist with cancer, often requiring a reduction in targeted therapy dosage. This systemat...

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Main Authors: Harri Hardi, Zahra Fitrianti, Karen Elliora Utama, Ananda Pipphali Vidya, Nurul Gusti Khatimah, Kevin Aristyo, Hana Khairina Putri Faisal, Vivian Soetikno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0324056
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