Unraveling the pathogenesis of Barrett’s esophagus and esophageal adenocarcinoma: the “omics” era

Unraveling the pathogenesis of Barrett’s esophagus and esophageal adenocarcinoma: the “omics” era

Barrett’s esophagus (BE) represents a pre-cancerous condition that is characterized by the metaplastic conversion of the squamous esophageal epithelium to a columnar intestinal-like phenotype. BE is the consequence of chronic reflux disease and has a potential progression burden to esophageal adenoc...

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Bibliographic Details
Main Authors: Alberto Barchi, Giuseppe Dell’Anna, Luca Massimino, Francesco Vito Mandarino, Edoardo Vespa, Edi Viale, Sandro Passaretti, Vito Annese, Alberto Malesci, Silvio Danese, Federica Ungaro
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Oncology
Subjects:
Barrett esophagus
esophageal cancer
metaplasia
omics
genomics
transcriptomics
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1458138/full
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