Molecular Analysis and Bioinformatics Assessment of Full-Length L1 Gene of Bovine Papillomavirus Type-1 as a Potential DNA Vaccine Study

Conclusions: The current investigation has provided crucial insights into BPV-1 type and diversity in the middle provinces of Iraq. These predominant strains have been identified and registered at NCBI for the first time. The amino acid mutations in the L1 protein have been highlighted. The conserve...

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Main Authors: Hassan Hadi Abdul-Zahra, Yahia I. Khudhair, Husam Raheem Al-Hraishawi
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Veterinary Medicine International
Online Access:http://dx.doi.org/10.1155/vmi/6785087
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author Hassan Hadi Abdul-Zahra
Yahia I. Khudhair
Husam Raheem Al-Hraishawi
author_facet Hassan Hadi Abdul-Zahra
Yahia I. Khudhair
Husam Raheem Al-Hraishawi
author_sort Hassan Hadi Abdul-Zahra
collection DOAJ
description Conclusions: The current investigation has provided crucial insights into BPV-1 type and diversity in the middle provinces of Iraq. These predominant strains have been identified and registered at NCBI for the first time. The amino acid mutations in the L1 protein have been highlighted. The conserved T- and B-cell epitopes that can detect BPV-1 type have been stablished. Finally, this project is the initial phase of creating a DNA-based vaccination for preventative and treatment purposes against BPV-related illnesses.
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series Veterinary Medicine International
spelling doaj-art-a86d3a3325bb479ebc6c22de46ec11452025-08-20T02:26:55ZengWileyVeterinary Medicine International2042-00482025-01-01202510.1155/vmi/6785087Molecular Analysis and Bioinformatics Assessment of Full-Length L1 Gene of Bovine Papillomavirus Type-1 as a Potential DNA Vaccine StudyHassan Hadi Abdul-Zahra0Yahia I. Khudhair1Husam Raheem Al-Hraishawi2Hillah Veterinary HospitalDepartment of Internal and Preventive MedicineDepartment of PhysiologyConclusions: The current investigation has provided crucial insights into BPV-1 type and diversity in the middle provinces of Iraq. These predominant strains have been identified and registered at NCBI for the first time. The amino acid mutations in the L1 protein have been highlighted. The conserved T- and B-cell epitopes that can detect BPV-1 type have been stablished. Finally, this project is the initial phase of creating a DNA-based vaccination for preventative and treatment purposes against BPV-related illnesses.http://dx.doi.org/10.1155/vmi/6785087
spellingShingle Hassan Hadi Abdul-Zahra
Yahia I. Khudhair
Husam Raheem Al-Hraishawi
Molecular Analysis and Bioinformatics Assessment of Full-Length L1 Gene of Bovine Papillomavirus Type-1 as a Potential DNA Vaccine Study
Veterinary Medicine International
title Molecular Analysis and Bioinformatics Assessment of Full-Length L1 Gene of Bovine Papillomavirus Type-1 as a Potential DNA Vaccine Study
title_full Molecular Analysis and Bioinformatics Assessment of Full-Length L1 Gene of Bovine Papillomavirus Type-1 as a Potential DNA Vaccine Study
title_fullStr Molecular Analysis and Bioinformatics Assessment of Full-Length L1 Gene of Bovine Papillomavirus Type-1 as a Potential DNA Vaccine Study
title_full_unstemmed Molecular Analysis and Bioinformatics Assessment of Full-Length L1 Gene of Bovine Papillomavirus Type-1 as a Potential DNA Vaccine Study
title_short Molecular Analysis and Bioinformatics Assessment of Full-Length L1 Gene of Bovine Papillomavirus Type-1 as a Potential DNA Vaccine Study
title_sort molecular analysis and bioinformatics assessment of full length l1 gene of bovine papillomavirus type 1 as a potential dna vaccine study
url http://dx.doi.org/10.1155/vmi/6785087
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AT husamraheemalhraishawi molecularanalysisandbioinformaticsassessmentoffulllengthl1geneofbovinepapillomavirustype1asapotentialdnavaccinestudy