C3G improves lipid droplet accumulation in the proximal tubules of high-fat diet-induced ORG mice

C3G improves lipid droplet accumulation in the proximal tubules of high-fat diet-induced ORG mice

Obesity-related glomerulopathy (ORG) represents an escalating public health with no effective treatments currently available. Abnormal lipid metabolism and lipid droplet deposition in the kidneys are key contributors to ORG. Cyanidin-3-glucoside (C3G) has shown potential in regulating lipid metaboli...

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Bibliographic Details
Main Authors: Yong-Ping Lu, Xiao-Hua Wang, Bin Xia, Hong-Wei Wu, Yan Lei, Kai-Wen Cai, Zi-Yan Deng, Chun Tang, Wei-Bin Bai, Ting Zhu, Zhi-Hua Zheng
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Pharmacological Research
Subjects:
Obesity-related glomerulopathy
Cyanidin-3-glucoside
Gut microbiota
Glycerophospholipid metabolism
Single-cell RNA sequencing
Online Access:http://www.sciencedirect.com/science/article/pii/S104366182400495X
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