Characterization of Seed Storage Proteins from Chickpea Using 2D Electrophoresis Coupled with Mass Spectrometry

Proteomic analysis was employed to map the seed storage protein network in landrace and cultivated chickpea accessions. Protein extracts were separated by two-dimensional gel electrophoresis (2D-GE) across a broad range 3.0–10.0 immobilized pH gradient (IPG) strips. Comparative elucidation of differ...

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Main Authors: Pramod Kumar Singh, Nidhi Shrivastava, Krishna Chaturvedi, Bechan Sharma, Sameer S. Bhagyawant
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Biochemistry Research International
Online Access:http://dx.doi.org/10.1155/2016/1049462
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author Pramod Kumar Singh
Nidhi Shrivastava
Krishna Chaturvedi
Bechan Sharma
Sameer S. Bhagyawant
author_facet Pramod Kumar Singh
Nidhi Shrivastava
Krishna Chaturvedi
Bechan Sharma
Sameer S. Bhagyawant
author_sort Pramod Kumar Singh
collection DOAJ
description Proteomic analysis was employed to map the seed storage protein network in landrace and cultivated chickpea accessions. Protein extracts were separated by two-dimensional gel electrophoresis (2D-GE) across a broad range 3.0–10.0 immobilized pH gradient (IPG) strips. Comparative elucidation of differentially expressed proteins between two diverse geographically originated chickpea accessions was carried out using 2D-GE coupled with mass spectrometry. A total of 600 protein spots were detected in these accessions. In-gel protein expression patterns revealed three protein spots as upregulated and three other as downregulated. Using trypsin in-gel digestion, these differentially expressed proteins were identified by matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF-MS) which showed 45% amino acid homology of chickpea seed storage proteins with Arabidopsis thaliana.
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institution Kabale University
issn 2090-2247
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publishDate 2016-01-01
publisher Wiley
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series Biochemistry Research International
spelling doaj-art-a8671b85ec9047f8b9dcc7571bf63d532025-08-20T03:38:54ZengWileyBiochemistry Research International2090-22472090-22552016-01-01201610.1155/2016/10494621049462Characterization of Seed Storage Proteins from Chickpea Using 2D Electrophoresis Coupled with Mass SpectrometryPramod Kumar Singh0Nidhi Shrivastava1Krishna Chaturvedi2Bechan Sharma3Sameer S. Bhagyawant4School of Studies in Biotechnology, Jiwaji University, Gwalior 474011, IndiaDepartment of Bioscience & Biotechnology, Banasthali University, Banasthali 304022, IndiaDefense Research & Development Establishment, Gwalior 474011, IndiaDepartment of Biochemistry, University of Allahabad, Allahabad 211002, IndiaSchool of Studies in Biotechnology, Jiwaji University, Gwalior 474011, IndiaProteomic analysis was employed to map the seed storage protein network in landrace and cultivated chickpea accessions. Protein extracts were separated by two-dimensional gel electrophoresis (2D-GE) across a broad range 3.0–10.0 immobilized pH gradient (IPG) strips. Comparative elucidation of differentially expressed proteins between two diverse geographically originated chickpea accessions was carried out using 2D-GE coupled with mass spectrometry. A total of 600 protein spots were detected in these accessions. In-gel protein expression patterns revealed three protein spots as upregulated and three other as downregulated. Using trypsin in-gel digestion, these differentially expressed proteins were identified by matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF-MS) which showed 45% amino acid homology of chickpea seed storage proteins with Arabidopsis thaliana.http://dx.doi.org/10.1155/2016/1049462
spellingShingle Pramod Kumar Singh
Nidhi Shrivastava
Krishna Chaturvedi
Bechan Sharma
Sameer S. Bhagyawant
Characterization of Seed Storage Proteins from Chickpea Using 2D Electrophoresis Coupled with Mass Spectrometry
Biochemistry Research International
title Characterization of Seed Storage Proteins from Chickpea Using 2D Electrophoresis Coupled with Mass Spectrometry
title_full Characterization of Seed Storage Proteins from Chickpea Using 2D Electrophoresis Coupled with Mass Spectrometry
title_fullStr Characterization of Seed Storage Proteins from Chickpea Using 2D Electrophoresis Coupled with Mass Spectrometry
title_full_unstemmed Characterization of Seed Storage Proteins from Chickpea Using 2D Electrophoresis Coupled with Mass Spectrometry
title_short Characterization of Seed Storage Proteins from Chickpea Using 2D Electrophoresis Coupled with Mass Spectrometry
title_sort characterization of seed storage proteins from chickpea using 2d electrophoresis coupled with mass spectrometry
url http://dx.doi.org/10.1155/2016/1049462
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