Antimicrobial effect of Dialkylcarbamoyl chloride (DACC) on infected surgical wounds. Experimental study
To evaluate the antimicrobial and histopathological effects of Dialkylcarbamoyl chloride (DACC) dressing on surgical wounds infected with various pathogens. In Group 1 (control), after the midline incision on interscapular region, wounds were closed with non–absorbable sutures in sterile conditions...
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Universidad del Zulia
2025-07-01
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| Series: | Revista Científica |
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| Online Access: | https://produccioncientificaluz.org/index.php/cientifica/article/view/44098 |
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| author | Hamdullah Suphi Bayraktar İlke Evrim Seçinti |
| author_facet | Hamdullah Suphi Bayraktar İlke Evrim Seçinti |
| author_sort | Hamdullah Suphi Bayraktar |
| collection | DOAJ |
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To evaluate the antimicrobial and histopathological effects of Dialkylcarbamoyl chloride (DACC) dressing on surgical wounds infected with various pathogens. In Group 1 (control), after the midline incision on interscapular region, wounds were closed with non–absorbable sutures in sterile conditions and nitrofurazone was applied externally to the surgical wounds. Wounds were covered with sterile gauze. In Group 2, 3, 4, and 5 rats were incised and wounds were contaminated with Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, and Candida albicans, respectively. Contaminated surgical wounds were covered with DACC dressing just after the incision. Dressings were changed every after 3 day. In all groups it was clearly seen that DACC showed antimicrobial effect against various microorganisms on surgical site infections. In 2nd group epithelial thickness of samples were decreased when compared to control group but it was no statistically significant. Also in this group fibrosis was statistically less than other groups. DACC covered dressing is a strategical biomechanic infection preventing material can be used against surgical site infection riscs safely. It has no any side effect known due to external uses. The hidrophobicity of DACC lets high binding capacity for microorganisms.
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| format | Article |
| id | doaj-art-a85b8ca891ff4ab4bab1430e0df22bbc |
| institution | Kabale University |
| issn | 0798-2259 2521-9715 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Universidad del Zulia |
| record_format | Article |
| series | Revista Científica |
| spelling | doaj-art-a85b8ca891ff4ab4bab1430e0df22bbc2025-08-20T03:28:09ZengUniversidad del ZuliaRevista Científica0798-22592521-97152025-07-0135310.52973/rcfcv-e35642Antimicrobial effect of Dialkylcarbamoyl chloride (DACC) on infected surgical wounds. Experimental studyHamdullah Suphi Bayraktar0İlke Evrim Seçinti1Hatay Mustafa Kemal University, Experimental Researches Application and Research Center. Hatay, Türkiye.Mersin University, Faculty of Medicine, Department of Medical Pathology. Mersin, Türkiye. To evaluate the antimicrobial and histopathological effects of Dialkylcarbamoyl chloride (DACC) dressing on surgical wounds infected with various pathogens. In Group 1 (control), after the midline incision on interscapular region, wounds were closed with non–absorbable sutures in sterile conditions and nitrofurazone was applied externally to the surgical wounds. Wounds were covered with sterile gauze. In Group 2, 3, 4, and 5 rats were incised and wounds were contaminated with Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, and Candida albicans, respectively. Contaminated surgical wounds were covered with DACC dressing just after the incision. Dressings were changed every after 3 day. In all groups it was clearly seen that DACC showed antimicrobial effect against various microorganisms on surgical site infections. In 2nd group epithelial thickness of samples were decreased when compared to control group but it was no statistically significant. Also in this group fibrosis was statistically less than other groups. DACC covered dressing is a strategical biomechanic infection preventing material can be used against surgical site infection riscs safely. It has no any side effect known due to external uses. The hidrophobicity of DACC lets high binding capacity for microorganisms. https://produccioncientificaluz.org/index.php/cientifica/article/view/44098Dialkylcarbamoyl chloridesurgical site infectionStaphylococcus aureusPseudomonas aeruginosa |
| spellingShingle | Hamdullah Suphi Bayraktar İlke Evrim Seçinti Antimicrobial effect of Dialkylcarbamoyl chloride (DACC) on infected surgical wounds. Experimental study Revista Científica Dialkylcarbamoyl chloride surgical site infection Staphylococcus aureus Pseudomonas aeruginosa |
| title | Antimicrobial effect of Dialkylcarbamoyl chloride (DACC) on infected surgical wounds. Experimental study |
| title_full | Antimicrobial effect of Dialkylcarbamoyl chloride (DACC) on infected surgical wounds. Experimental study |
| title_fullStr | Antimicrobial effect of Dialkylcarbamoyl chloride (DACC) on infected surgical wounds. Experimental study |
| title_full_unstemmed | Antimicrobial effect of Dialkylcarbamoyl chloride (DACC) on infected surgical wounds. Experimental study |
| title_short | Antimicrobial effect of Dialkylcarbamoyl chloride (DACC) on infected surgical wounds. Experimental study |
| title_sort | antimicrobial effect of dialkylcarbamoyl chloride dacc on infected surgical wounds experimental study |
| topic | Dialkylcarbamoyl chloride surgical site infection Staphylococcus aureus Pseudomonas aeruginosa |
| url | https://produccioncientificaluz.org/index.php/cientifica/article/view/44098 |
| work_keys_str_mv | AT hamdullahsuphibayraktar antimicrobialeffectofdialkylcarbamoylchloridedacconinfectedsurgicalwoundsexperimentalstudy AT ilkeevrimsecinti antimicrobialeffectofdialkylcarbamoylchloridedacconinfectedsurgicalwoundsexperimentalstudy |