Drug-coated Balloons for Small Coronary Vessel Interventions: A Literature Review

Newer-generation drug-eluting stents (DES) are the standard of care for the treatment of symptomatic coronary artery disease. However, some lack of efficacy has been reported in small coronary arteries based on higher rates of target lesion restenosis, thrombosis and MI resulting in repeated interve...

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Main Authors: Thomas Nestelberger, Raban Jeger
Format: Article
Language:English
Published: Radcliffe Medical Media 2019-11-01
Series:Interventional Cardiology: Reviews, Research, Resources
Online Access:https://www.icrjournal.com/articles/Drug-coated-Balloons-for-Small-Coronary-Vessel-Interventions
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author Thomas Nestelberger
Raban Jeger
author_facet Thomas Nestelberger
Raban Jeger
author_sort Thomas Nestelberger
collection DOAJ
description Newer-generation drug-eluting stents (DES) are the standard of care for the treatment of symptomatic coronary artery disease. However, some lack of efficacy has been reported in small coronary arteries based on higher rates of target lesion restenosis, thrombosis and MI resulting in repeated interventions. Drug-coated balloons (DCBs) are an established treatment option for in-stent restenosis in both bare metal stents and DES and they can deliver an anti-proliferative drug into the vessel wall without implanting a stent. DCBs are a promising technique for selected de novo coronary lesions, especially in small vessel disease. In this article, the current evidence for the treatment of small vessel disease with DCBs will be reviewed.
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publishDate 2019-11-01
publisher Radcliffe Medical Media
record_format Article
series Interventional Cardiology: Reviews, Research, Resources
spelling doaj-art-a85a360d94004ca09b01c75d29e3f7fa2025-08-20T01:56:38ZengRadcliffe Medical MediaInterventional Cardiology: Reviews, Research, Resources1756-14771756-14852019-11-0114313113610.15420/icr.2019.06.R3Drug-coated Balloons for Small Coronary Vessel Interventions: A Literature ReviewThomas Nestelberger0Raban Jeger1Cardiovascular Research Institute Basel (CRIB) and Department of Cardiology, University Hospital Basel, University of Basel, SwitzerlandCardiovascular Research Institute Basel (CRIB) and Department of Cardiology, University Hospital Basel, University of Basel, SwitzerlandNewer-generation drug-eluting stents (DES) are the standard of care for the treatment of symptomatic coronary artery disease. However, some lack of efficacy has been reported in small coronary arteries based on higher rates of target lesion restenosis, thrombosis and MI resulting in repeated interventions. Drug-coated balloons (DCBs) are an established treatment option for in-stent restenosis in both bare metal stents and DES and they can deliver an anti-proliferative drug into the vessel wall without implanting a stent. DCBs are a promising technique for selected de novo coronary lesions, especially in small vessel disease. In this article, the current evidence for the treatment of small vessel disease with DCBs will be reviewed.https://www.icrjournal.com/articles/Drug-coated-Balloons-for-Small-Coronary-Vessel-Interventions
spellingShingle Thomas Nestelberger
Raban Jeger
Drug-coated Balloons for Small Coronary Vessel Interventions: A Literature Review
Interventional Cardiology: Reviews, Research, Resources
title Drug-coated Balloons for Small Coronary Vessel Interventions: A Literature Review
title_full Drug-coated Balloons for Small Coronary Vessel Interventions: A Literature Review
title_fullStr Drug-coated Balloons for Small Coronary Vessel Interventions: A Literature Review
title_full_unstemmed Drug-coated Balloons for Small Coronary Vessel Interventions: A Literature Review
title_short Drug-coated Balloons for Small Coronary Vessel Interventions: A Literature Review
title_sort drug coated balloons for small coronary vessel interventions a literature review
url https://www.icrjournal.com/articles/Drug-coated-Balloons-for-Small-Coronary-Vessel-Interventions
work_keys_str_mv AT thomasnestelberger drugcoatedballoonsforsmallcoronaryvesselinterventionsaliteraturereview
AT rabanjeger drugcoatedballoonsforsmallcoronaryvesselinterventionsaliteraturereview