Laparoscopic Splenectomy for Hairy Cell Leukemia in Pregnancy

Objective. We present a successful case of laparoscopic splenectomy for a massively enlarged spleen at 25 weeks of gestation for hairy cell leukemia in pregnancy in a woman with initial hemoglobin of 4.3 gm/dl and platelet count of 18,000/mm3. Study Design. Case report. Results. This report provides...

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Main Authors: Beni Adegoke Adeniji, Moses Fallas, Marc Incerpi, Solomon Hamburg, Robert Katz, Dotun Ogunyemi
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2010/136823
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author Beni Adegoke Adeniji
Moses Fallas
Marc Incerpi
Solomon Hamburg
Robert Katz
Dotun Ogunyemi
author_facet Beni Adegoke Adeniji
Moses Fallas
Marc Incerpi
Solomon Hamburg
Robert Katz
Dotun Ogunyemi
author_sort Beni Adegoke Adeniji
collection DOAJ
description Objective. We present a successful case of laparoscopic splenectomy for a massively enlarged spleen at 25 weeks of gestation for hairy cell leukemia in pregnancy in a woman with initial hemoglobin of 4.3 gm/dl and platelet count of 18,000/mm3. Study Design. Case report. Results. This report provides an approach to management that may be applicable in those cases where thrombocytopenia or other clinical imperatives preclude delaying treatment till after pregnancy. Conclusion. Hairy cell leukemia is a clonal B-Cell malignancy, for which there is very limited experience worldwide for its management when it occurs during pregnancy. Laparoscopic splenectomy should be considered as a therapeutic option, even with a significantly enlarged spleen, in order to avoid the risks of fetal exposure to chemotherapeutic agents. Unique considerations relating to pregnancy are highlighted.
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institution Kabale University
issn 1687-9627
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publishDate 2010-01-01
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series Case Reports in Medicine
spelling doaj-art-a85a235f3523474583bafa5921ee94cc2025-02-03T00:59:29ZengWileyCase Reports in Medicine1687-96271687-96352010-01-01201010.1155/2010/136823136823Laparoscopic Splenectomy for Hairy Cell Leukemia in PregnancyBeni Adegoke Adeniji0Moses Fallas1Marc Incerpi2Solomon Hamburg3Robert Katz4Dotun Ogunyemi5Cedars-Sinai Medical Center, 8700 W Beverly Bowerard, Los Angeles, CA 90048, USACedars-Sinai Medical Center, 8700 W Beverly Bowerard, Los Angeles, CA 90048, USALAC+USC Medical Center, 1420 S Central Avenue, Glendale, CA 91201, USACedars-Sinai Medical Center, 8700 W Beverly Bowerard, Los Angeles, CA 90048, USACedars-Sinai Medical Center, 8700 W Beverly Bowerard, Los Angeles, CA 90048, USACedars-Sinai Medical Center, 8700 W Beverly Bowerard, Los Angeles, CA 90048, USAObjective. We present a successful case of laparoscopic splenectomy for a massively enlarged spleen at 25 weeks of gestation for hairy cell leukemia in pregnancy in a woman with initial hemoglobin of 4.3 gm/dl and platelet count of 18,000/mm3. Study Design. Case report. Results. This report provides an approach to management that may be applicable in those cases where thrombocytopenia or other clinical imperatives preclude delaying treatment till after pregnancy. Conclusion. Hairy cell leukemia is a clonal B-Cell malignancy, for which there is very limited experience worldwide for its management when it occurs during pregnancy. Laparoscopic splenectomy should be considered as a therapeutic option, even with a significantly enlarged spleen, in order to avoid the risks of fetal exposure to chemotherapeutic agents. Unique considerations relating to pregnancy are highlighted.http://dx.doi.org/10.1155/2010/136823
spellingShingle Beni Adegoke Adeniji
Moses Fallas
Marc Incerpi
Solomon Hamburg
Robert Katz
Dotun Ogunyemi
Laparoscopic Splenectomy for Hairy Cell Leukemia in Pregnancy
Case Reports in Medicine
title Laparoscopic Splenectomy for Hairy Cell Leukemia in Pregnancy
title_full Laparoscopic Splenectomy for Hairy Cell Leukemia in Pregnancy
title_fullStr Laparoscopic Splenectomy for Hairy Cell Leukemia in Pregnancy
title_full_unstemmed Laparoscopic Splenectomy for Hairy Cell Leukemia in Pregnancy
title_short Laparoscopic Splenectomy for Hairy Cell Leukemia in Pregnancy
title_sort laparoscopic splenectomy for hairy cell leukemia in pregnancy
url http://dx.doi.org/10.1155/2010/136823
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