Cell-cycle and Apoptosis Regulators (p16INK4A, p21CIP1, α-Catenin, Survivin, and hTERT) and Morphometry-Defined MPECs Predict Metachronous Cancer Development in Colorectal Adenoma Patients
Background and Aims: Although adenomas may be precursors to colorectal cancers (CRC), knowledge concerning the development of metachronous CRC is scarce. We assessed whether differential expression of cell-cycle and apoptosis-regulating proteins and a monotonous population of elongated cells (MPECs)...
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| Main Authors: | Kjetil Soreide, Tirza C. E. Buter, Emiel A. Janssen, Einar Gudlaugsson, Ivar Skaland, Hartwig Körner, Jan P. A. Baak |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2007-01-01
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| Series: | Cellular Oncology |
| Online Access: | http://dx.doi.org/10.1155/2007/457427 |
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