Cerebral Salt Wasting Syndrome Caused by Severe Traumatic Brain Injury in a Pediatric Patient and Review of the Literature

Background. Following acute traumatic brain injury, cerebral salt wasting (CSW) syndrome is considered as an important cause of hyponatremia apart from syndrome of inappropriate antidiuretic hormone. Differentiation between the two syndromes is crucial for the initiation of an adequate treatment. Ca...

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Main Authors: Mohamed Aziz Daghmouri, Maroua Ouesleti, Mohamed Amine Touati, Olfa Faten, Sameh Zakhama, Lotfi Rebai
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Critical Care
Online Access:http://dx.doi.org/10.1155/2021/6679279
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author Mohamed Aziz Daghmouri
Maroua Ouesleti
Mohamed Amine Touati
Olfa Faten
Sameh Zakhama
Lotfi Rebai
author_facet Mohamed Aziz Daghmouri
Maroua Ouesleti
Mohamed Amine Touati
Olfa Faten
Sameh Zakhama
Lotfi Rebai
author_sort Mohamed Aziz Daghmouri
collection DOAJ
description Background. Following acute traumatic brain injury, cerebral salt wasting (CSW) syndrome is considered as an important cause of hyponatremia apart from syndrome of inappropriate antidiuretic hormone. Differentiation between the two syndromes is crucial for the initiation of an adequate treatment. Case Presentation. We report a 15-year-old female adolescent, admitted to intensive care for acute severe traumatic brain injury. During his hospitalization, she developed a hyponatremia with an increase of urine output and hypovolemia. So, the most probable diagnosis was CSW. Initially, she was treated by hypertonic saline and volume expansion. However, his sodium level continued to fall despite infusion of hypertonic saline. That is why fludrocortisone was introduced initially at 50 μg/day then increased to 150 μg/day. Fludrocortisone was continued for the next months. Serum sodium level was 138 mmol/L after one month of treatment. Conclusion. Hyponatremia may occur after severe traumatic brain injury that is why an adequate treatment initiated on time is necessary in order to reduce morbidity and mortality.
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spelling doaj-art-a854197f3f87462cbbede32af6eaebf72025-08-20T02:20:44ZengWileyCase Reports in Critical Care2090-64202090-64392021-01-01202110.1155/2021/66792796679279Cerebral Salt Wasting Syndrome Caused by Severe Traumatic Brain Injury in a Pediatric Patient and Review of the LiteratureMohamed Aziz Daghmouri0Maroua Ouesleti1Mohamed Amine Touati2Olfa Faten3Sameh Zakhama4Lotfi Rebai5Department of Anesthesia, Trauma Center of Ben Arrous, TunisiaDepartment of Anesthesia, Trauma Center of Ben Arrous, TunisiaDepartment of Anesthesia, Trauma Center of Ben Arrous, TunisiaDepartment of Anesthesia, Trauma Center of Ben Arrous, TunisiaDepartment of Anesthesia, Trauma Center of Ben Arrous, TunisiaDepartment of Anesthesia, Trauma Center of Ben Arrous, TunisiaBackground. Following acute traumatic brain injury, cerebral salt wasting (CSW) syndrome is considered as an important cause of hyponatremia apart from syndrome of inappropriate antidiuretic hormone. Differentiation between the two syndromes is crucial for the initiation of an adequate treatment. Case Presentation. We report a 15-year-old female adolescent, admitted to intensive care for acute severe traumatic brain injury. During his hospitalization, she developed a hyponatremia with an increase of urine output and hypovolemia. So, the most probable diagnosis was CSW. Initially, she was treated by hypertonic saline and volume expansion. However, his sodium level continued to fall despite infusion of hypertonic saline. That is why fludrocortisone was introduced initially at 50 μg/day then increased to 150 μg/day. Fludrocortisone was continued for the next months. Serum sodium level was 138 mmol/L after one month of treatment. Conclusion. Hyponatremia may occur after severe traumatic brain injury that is why an adequate treatment initiated on time is necessary in order to reduce morbidity and mortality.http://dx.doi.org/10.1155/2021/6679279
spellingShingle Mohamed Aziz Daghmouri
Maroua Ouesleti
Mohamed Amine Touati
Olfa Faten
Sameh Zakhama
Lotfi Rebai
Cerebral Salt Wasting Syndrome Caused by Severe Traumatic Brain Injury in a Pediatric Patient and Review of the Literature
Case Reports in Critical Care
title Cerebral Salt Wasting Syndrome Caused by Severe Traumatic Brain Injury in a Pediatric Patient and Review of the Literature
title_full Cerebral Salt Wasting Syndrome Caused by Severe Traumatic Brain Injury in a Pediatric Patient and Review of the Literature
title_fullStr Cerebral Salt Wasting Syndrome Caused by Severe Traumatic Brain Injury in a Pediatric Patient and Review of the Literature
title_full_unstemmed Cerebral Salt Wasting Syndrome Caused by Severe Traumatic Brain Injury in a Pediatric Patient and Review of the Literature
title_short Cerebral Salt Wasting Syndrome Caused by Severe Traumatic Brain Injury in a Pediatric Patient and Review of the Literature
title_sort cerebral salt wasting syndrome caused by severe traumatic brain injury in a pediatric patient and review of the literature
url http://dx.doi.org/10.1155/2021/6679279
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