Future Therapies of Wet Age-Related Macular Degeneration
Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly population, and the prevalence of the disease increases exponentially with every decade after the age of 50 years. While VEGF inhibitors are promising drugs for treating patients with ocular neovascularization, t...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2015/138070 |
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| _version_ | 1832554168573755392 |
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| author | Makoto Ishikawa Daisuke Jin Yu Sawada Sanae Abe Takeshi Yoshitomi |
| author_facet | Makoto Ishikawa Daisuke Jin Yu Sawada Sanae Abe Takeshi Yoshitomi |
| author_sort | Makoto Ishikawa |
| collection | DOAJ |
| description | Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly population, and the prevalence of the disease increases exponentially with every decade after the age of 50 years. While VEGF inhibitors are promising drugs for treating patients with ocular neovascularization, there are limitations to their potential for improving vision in AMD patients. Thus, future therapies are required to have the potential to improve visual outcomes. This paper will summarize the future strategies and therapeutic targets that are aimed at enhancing the efficacy and duration of effect of antiangiogenic strategies. |
| format | Article |
| id | doaj-art-a84925140df44766896c58c66a48c316 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-a84925140df44766896c58c66a48c3162025-02-03T05:52:18ZengWileyJournal of Ophthalmology2090-004X2090-00582015-01-01201510.1155/2015/138070138070Future Therapies of Wet Age-Related Macular DegenerationMakoto Ishikawa0Daisuke Jin1Yu Sawada2Sanae Abe3Takeshi Yoshitomi4Department of Ophthalmology, Akita Graduate University School of Medicine, Akita 010-8543, JapanDepartment of Ophthalmology, Akita Graduate University School of Medicine, Akita 010-8543, JapanDepartment of Ophthalmology, Akita Graduate University School of Medicine, Akita 010-8543, JapanDepartment of Ophthalmology, Akita Graduate University School of Medicine, Akita 010-8543, JapanDepartment of Ophthalmology, Akita Graduate University School of Medicine, Akita 010-8543, JapanAge-related macular degeneration (AMD) is the leading cause of blindness in the elderly population, and the prevalence of the disease increases exponentially with every decade after the age of 50 years. While VEGF inhibitors are promising drugs for treating patients with ocular neovascularization, there are limitations to their potential for improving vision in AMD patients. Thus, future therapies are required to have the potential to improve visual outcomes. This paper will summarize the future strategies and therapeutic targets that are aimed at enhancing the efficacy and duration of effect of antiangiogenic strategies.http://dx.doi.org/10.1155/2015/138070 |
| spellingShingle | Makoto Ishikawa Daisuke Jin Yu Sawada Sanae Abe Takeshi Yoshitomi Future Therapies of Wet Age-Related Macular Degeneration Journal of Ophthalmology |
| title | Future Therapies of Wet Age-Related Macular Degeneration |
| title_full | Future Therapies of Wet Age-Related Macular Degeneration |
| title_fullStr | Future Therapies of Wet Age-Related Macular Degeneration |
| title_full_unstemmed | Future Therapies of Wet Age-Related Macular Degeneration |
| title_short | Future Therapies of Wet Age-Related Macular Degeneration |
| title_sort | future therapies of wet age related macular degeneration |
| url | http://dx.doi.org/10.1155/2015/138070 |
| work_keys_str_mv | AT makotoishikawa futuretherapiesofwetagerelatedmaculardegeneration AT daisukejin futuretherapiesofwetagerelatedmaculardegeneration AT yusawada futuretherapiesofwetagerelatedmaculardegeneration AT sanaeabe futuretherapiesofwetagerelatedmaculardegeneration AT takeshiyoshitomi futuretherapiesofwetagerelatedmaculardegeneration |