Modifiable prognostic factors in uterine fibroid development: a systematic review of literature
Background Many risk factors in uterine fibroid development have been identified, but women and their physicians are less aware of the influence of lifestyle on uterine fibroid development. The objective of this systematic review is to investigate and summarize modifiable prognostic factors associat...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | Journal of Obstetrics and Gynaecology |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/01443615.2023.2288225 |
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| author | Alieke L. Keizer Annika Semmler Helen S. Kok Paul J.M van Kesteren Judith A.F Huirne Wouter J.K Hehenkamp |
| author_facet | Alieke L. Keizer Annika Semmler Helen S. Kok Paul J.M van Kesteren Judith A.F Huirne Wouter J.K Hehenkamp |
| author_sort | Alieke L. Keizer |
| collection | DOAJ |
| description | Background Many risk factors in uterine fibroid development have been identified, but women and their physicians are less aware of the influence of lifestyle on uterine fibroid development. The objective of this systematic review is to investigate and summarize modifiable prognostic factors associated with uterine fibroid development.Methods Pubmed and Embase were searched for relevant articles according to PRISMA guidelines. References from included articles were screened and when relevant also included. Human in vivo studies on modifiable factors in fibroid development were included. Studies on non-modifiable factors and treatment, in vitro studies and animal studies were excluded. 607 articles were screened and 33 articles were included. Two independent investigators collected data from the report.Results The strongest risk factor for fibroid development was a high BMI, while the strongest protective factors were a high fruit and vegetable intake and high vitamin D intake.Conclusion More high-quality studies are necessary to better understand the impact of the abovementioned factors as well as the role they play in the growth of already existing fibroids. |
| format | Article |
| id | doaj-art-a82dfb47748449558621ada47c75ef3d |
| institution | Kabale University |
| issn | 0144-3615 1364-6893 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Obstetrics and Gynaecology |
| spelling | doaj-art-a82dfb47748449558621ada47c75ef3d2025-01-09T12:13:17ZengTaylor & Francis GroupJournal of Obstetrics and Gynaecology0144-36151364-68932024-12-0144110.1080/01443615.2023.2288225Modifiable prognostic factors in uterine fibroid development: a systematic review of literatureAlieke L. Keizer0Annika Semmler1Helen S. Kok2Paul J.M van Kesteren3Judith A.F Huirne4Wouter J.K Hehenkamp5Department of Obstetrics and Gynaecology, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam Reproduction and Development Research Institute, Amsterdam, The NetherlandsDepartment of Obstetrics and Gynaecology, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam Reproduction and Development Research Institute, Amsterdam, The NetherlandsDepartment of Obstetrics and Gynaecology, Alrijne Ziekenhuis location Leiden, Leiden, The NetherlandsOLVG Location East, Department of Obstetrics and Gynaecology, Amsterdam, The NetherlandsDepartment of Obstetrics and Gynaecology, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam Reproduction and Development Research Institute, Amsterdam, The NetherlandsDepartment of Obstetrics and Gynaecology, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam Reproduction and Development Research Institute, Amsterdam, The NetherlandsBackground Many risk factors in uterine fibroid development have been identified, but women and their physicians are less aware of the influence of lifestyle on uterine fibroid development. The objective of this systematic review is to investigate and summarize modifiable prognostic factors associated with uterine fibroid development.Methods Pubmed and Embase were searched for relevant articles according to PRISMA guidelines. References from included articles were screened and when relevant also included. Human in vivo studies on modifiable factors in fibroid development were included. Studies on non-modifiable factors and treatment, in vitro studies and animal studies were excluded. 607 articles were screened and 33 articles were included. Two independent investigators collected data from the report.Results The strongest risk factor for fibroid development was a high BMI, while the strongest protective factors were a high fruit and vegetable intake and high vitamin D intake.Conclusion More high-quality studies are necessary to better understand the impact of the abovementioned factors as well as the role they play in the growth of already existing fibroids.https://www.tandfonline.com/doi/10.1080/01443615.2023.2288225Uterine fibroidmodifiableprognostic factorrisk factor |
| spellingShingle | Alieke L. Keizer Annika Semmler Helen S. Kok Paul J.M van Kesteren Judith A.F Huirne Wouter J.K Hehenkamp Modifiable prognostic factors in uterine fibroid development: a systematic review of literature Journal of Obstetrics and Gynaecology Uterine fibroid modifiable prognostic factor risk factor |
| title | Modifiable prognostic factors in uterine fibroid development: a systematic review of literature |
| title_full | Modifiable prognostic factors in uterine fibroid development: a systematic review of literature |
| title_fullStr | Modifiable prognostic factors in uterine fibroid development: a systematic review of literature |
| title_full_unstemmed | Modifiable prognostic factors in uterine fibroid development: a systematic review of literature |
| title_short | Modifiable prognostic factors in uterine fibroid development: a systematic review of literature |
| title_sort | modifiable prognostic factors in uterine fibroid development a systematic review of literature |
| topic | Uterine fibroid modifiable prognostic factor risk factor |
| url | https://www.tandfonline.com/doi/10.1080/01443615.2023.2288225 |
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