Molecular assessment of NMDAR subunits and neuronal apoptosis in the trigeminal ganglion in a model of male migraine-induced rats following Moringa oleifera alcoholic extract administration

Molecular assessment of NMDAR subunits and neuronal apoptosis in the trigeminal ganglion in a model of male migraine-induced rats following Moringa oleifera alcoholic extract administration

Abstract Introduction Migraine, a common disorder marked by severe and repetitive headaches, has been linked to the involvement of the NMDA receptor (NMDAR), a receptor responsible for glutamate signaling. Moringa oleifera (M. oleifera), recognized for its anti-inflammatory properties and therapeuti...

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Bibliographic Details
Main Authors: Ahmad Vafaeian, Ali Vafaei, Mohammad Reza Parvizi, Mohsen Chamanara, Mojgan Mehriardestani, Yasaman Hosseini
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Neuroscience
Subjects:
Moringa Oleifera
Nr2a
Nr2b
Caspase-3
Bcl-2
Bax
Online Access:https://doi.org/10.1186/s12868-025-00928-w
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