Alloreactive-free CAR-VST therapy: a step forward in long-term tumor control in viral context

Alloreactive-free CAR-VST therapy: a step forward in long-term tumor control in viral context

CAR-T cell therapy has revolutionized immunotherapy but its allogeneic application, using various strategies, faces significant challenges including graft-versus-host disease and graft rejection. Recent advances using Virus Specific T cells to generate CAR-VST have demonstrated potential for enhance...

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Bibliographic Details
Main Authors: Valentine Wang, Barbara Savoldo, José-Arthur Guimaraes, Gianpietro Dotti, Loïc Reppel, Danièle Bensoussan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
CAR-T
virus specific T cell
CAR-VST
allogeneic
GvHD
graft rejection
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1527648/full
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