Characterization of a novel covS SNP identified in Australian group A Streptococcus isolates derived from the M1UK lineage

Characterization of a novel covS SNP identified in Australian group A Streptococcus isolates derived from the M1UK lineage

ABSTRACT Group A Streptococcus (GAS) is a human-adapted pathogen responsible for a variety of diseases. The GAS M1UK lineage has contributed significantly to the recently reported increases in scarlet fever and invasive infections. However, the basis for its evolutionary success is not yet fully und...

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Main Authors: Johanna Richter, Amanda J. Cork, Yvette Ong, Nadia Keller, Andrew J. Hayes, Mark A. Schembri, Amy V. Jennison, Mark R. Davies, Kate Schroder, Mark J. Walker, Stephan Brouwer
Format: Article
Language:English
Published: American Society for Microbiology 2025-02-01
Series:mBio
Subjects:
Streptococcus pyogenes
two-component system
CovRS
SNP
transcriptional regulation
SLO
Online Access:https://journals.asm.org/doi/10.1128/mbio.03366-24
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