Exercise Stress Testing in Children with Metabolic or Neuromuscular Disorders
The role of exercise as a diagnostic or therapeutic tool in patients with a metabolic disease (MD) or neuromuscular disorder (NMD) is relatively underresearched. In this paper we describe the metabolic profiles during exercise in 13 children (9 boys, 4 girls, age 5–15 yrs) with a diagnosed MD or NM...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2010-01-01
|
| Series: | International Journal of Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2010/254829 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832565187935207424 |
|---|---|
| author | Tim Takken Wim G. Groen Erik H. Hulzebos Cornelia G. Ernsting Peter M. van Hasselt Berthil H. Prinsen Paul J. Helders Gepke Visser |
| author_facet | Tim Takken Wim G. Groen Erik H. Hulzebos Cornelia G. Ernsting Peter M. van Hasselt Berthil H. Prinsen Paul J. Helders Gepke Visser |
| author_sort | Tim Takken |
| collection | DOAJ |
| description | The role of exercise as a diagnostic or therapeutic tool in patients with a metabolic disease (MD) or neuromuscular disorder (NMD) is relatively underresearched. In this paper we describe the metabolic profiles during exercise in 13 children (9 boys, 4 girls, age 5–15 yrs) with a diagnosed MD or NMD. Graded cardiopulmonary exercise tests and/or a 90-min prolonged submaximal exercise test were performed. During exercise, respiratory gas-exchange and heart rate were monitored; blood and urine samples were collected for biochemical analysis at set time points. Several characteristics in our patient group were observed, which reflected the differences in pathophysiology of the various disorders. Metabolic profiles during exercises CPET and PXT seem helpful in the evaluation of patients with a MD or NMD. |
| format | Article |
| id | doaj-art-a7fdb03a0ae54c6bb8249e712e2e707a |
| institution | Kabale University |
| issn | 1687-9740 1687-9759 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Pediatrics |
| spelling | doaj-art-a7fdb03a0ae54c6bb8249e712e2e707a2025-02-03T01:09:08ZengWileyInternational Journal of Pediatrics1687-97401687-97592010-01-01201010.1155/2010/254829254829Exercise Stress Testing in Children with Metabolic or Neuromuscular DisordersTim Takken0Wim G. Groen1Erik H. Hulzebos2Cornelia G. Ernsting3Peter M. van Hasselt4Berthil H. Prinsen5Paul J. Helders6Gepke Visser7Child Development and Exercise Center, Wilhelmina Children's Hospital, University Medical Center Utrecht, NL 3508 AB Utrecht, The NetherlandsChild Development and Exercise Center, Wilhelmina Children's Hospital, University Medical Center Utrecht, NL 3508 AB Utrecht, The NetherlandsChild Development and Exercise Center, Wilhelmina Children's Hospital, University Medical Center Utrecht, NL 3508 AB Utrecht, The NetherlandsFaculty of Medicine, Vrije University Medical Center, NL 1007 MB Amsterdam, The NetherlandsDepartment of Metabolic Diseases, Wilhelmina Children's Hospital, University Medical Center Utrecht, NL 3508 AB Utrecht, The NetherlandsDepartment of Metabolic and Endocrine Diseases, Wilhelmina Children's Hospital, University Medical Center Utrecht, NL 3508 AB Utrecht, The NetherlandsChild Development and Exercise Center, Wilhelmina Children's Hospital, University Medical Center Utrecht, NL 3508 AB Utrecht, The NetherlandsDepartment of Metabolic Diseases, Wilhelmina Children's Hospital, University Medical Center Utrecht, NL 3508 AB Utrecht, The NetherlandsThe role of exercise as a diagnostic or therapeutic tool in patients with a metabolic disease (MD) or neuromuscular disorder (NMD) is relatively underresearched. In this paper we describe the metabolic profiles during exercise in 13 children (9 boys, 4 girls, age 5–15 yrs) with a diagnosed MD or NMD. Graded cardiopulmonary exercise tests and/or a 90-min prolonged submaximal exercise test were performed. During exercise, respiratory gas-exchange and heart rate were monitored; blood and urine samples were collected for biochemical analysis at set time points. Several characteristics in our patient group were observed, which reflected the differences in pathophysiology of the various disorders. Metabolic profiles during exercises CPET and PXT seem helpful in the evaluation of patients with a MD or NMD.http://dx.doi.org/10.1155/2010/254829 |
| spellingShingle | Tim Takken Wim G. Groen Erik H. Hulzebos Cornelia G. Ernsting Peter M. van Hasselt Berthil H. Prinsen Paul J. Helders Gepke Visser Exercise Stress Testing in Children with Metabolic or Neuromuscular Disorders International Journal of Pediatrics |
| title | Exercise Stress Testing in Children with Metabolic or Neuromuscular Disorders |
| title_full | Exercise Stress Testing in Children with Metabolic or Neuromuscular Disorders |
| title_fullStr | Exercise Stress Testing in Children with Metabolic or Neuromuscular Disorders |
| title_full_unstemmed | Exercise Stress Testing in Children with Metabolic or Neuromuscular Disorders |
| title_short | Exercise Stress Testing in Children with Metabolic or Neuromuscular Disorders |
| title_sort | exercise stress testing in children with metabolic or neuromuscular disorders |
| url | http://dx.doi.org/10.1155/2010/254829 |
| work_keys_str_mv | AT timtakken exercisestresstestinginchildrenwithmetabolicorneuromusculardisorders AT wimggroen exercisestresstestinginchildrenwithmetabolicorneuromusculardisorders AT erikhhulzebos exercisestresstestinginchildrenwithmetabolicorneuromusculardisorders AT corneliagernsting exercisestresstestinginchildrenwithmetabolicorneuromusculardisorders AT petermvanhasselt exercisestresstestinginchildrenwithmetabolicorneuromusculardisorders AT berthilhprinsen exercisestresstestinginchildrenwithmetabolicorneuromusculardisorders AT pauljhelders exercisestresstestinginchildrenwithmetabolicorneuromusculardisorders AT gepkevisser exercisestresstestinginchildrenwithmetabolicorneuromusculardisorders |