Prevalence of traditional cardiovascular risk factors in high-risk Kyrgyzstan population as compared to Indians − An Indo-Kyrgyz cardiometabolic study

Background: Cardiovascular diseases (CVDs) are one of the most prevalent causes of mortality worldwide, especially significant in low- and middle-income countries. Kyrgyzstan and India represent such nations that face a huge burden of CVD-related deaths globally. Understanding the prevalence of trad...

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Main Authors: Kamal Sharma, Shilpi Mohan, S. A. Hossain, Stuti Shah, Ashwati Konat, Komal Shah, Shubh Mehta, Jonsi Jayantkumar Tavethia, Jeel Narendra Sarvaiya, Saumya Joshi, Karan Shah, Dhruv Rakeshkumar Patel, Shlok Patel
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Journal of Family Medicine and Primary Care
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Online Access:https://journals.lww.com/10.4103/jfmpc.jfmpc_712_24
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author Kamal Sharma
Shilpi Mohan
S. A. Hossain
Stuti Shah
Ashwati Konat
Komal Shah
Shubh Mehta
Jonsi Jayantkumar Tavethia
Jeel Narendra Sarvaiya
Saumya Joshi
Karan Shah
Dhruv Rakeshkumar Patel
Shlok Patel
author_facet Kamal Sharma
Shilpi Mohan
S. A. Hossain
Stuti Shah
Ashwati Konat
Komal Shah
Shubh Mehta
Jonsi Jayantkumar Tavethia
Jeel Narendra Sarvaiya
Saumya Joshi
Karan Shah
Dhruv Rakeshkumar Patel
Shlok Patel
author_sort Kamal Sharma
collection DOAJ
description Background: Cardiovascular diseases (CVDs) are one of the most prevalent causes of mortality worldwide, especially significant in low- and middle-income countries. Kyrgyzstan and India represent such nations that face a huge burden of CVD-related deaths globally. Understanding the prevalence of traditional cardiovascular risk factors (CVRFs) in these populations is critical for effective prevention and management strategies. Methods: This is a multicentric, observational study where we compared the prevalence of CVRFs in high-risk populations from Kyrgyzstan and India. Data was collected from established ASCVD patients attending cardio-metabolic clinics at tertiary care centers between December 2021 and December 2023. Demographic characteristics and CVRFs, which encompassed diabetes, hypertension, lipid profile parameters, tobacco consumption, etc., were assessed. Statistical analysis was performed to identify significant differences between the cohorts. Results: A total of 1552 individuals (772 from Kyrgyzstan, 750 from India) were studied. The Kyrgyzstan cohort had a significantly higher mean age and a greater proportion of females compared to the Indian cohort. The prevalence of tobacco consumption, hypertension, and diabetes was significantly higher in Kyrgyzstan than in India. Lipid profile analysis revealed greater level of LDL, HDL, and total cholesterol in the Kyrgyzstan cohort. Conversely, triglyceride levels were lower in Kyrgyz individuals. The Kyrgyzstan cohort also demonstrated better left ventricular systolic function compared to the Indian cohort. Discussion: Our study highlights significant differences in the prevalence of traditional CVRFs between high-risk populations in Kyrgyzstan and India. Higher rates of tobacco consumption, hypertension, and diabetes in Kyrgyzstan signify the immediate need for targeted interventions to address these modifiable risk factors. Targeted public health programs focusing on these lifestyle modifications and efficacious management of CVRFs are crucial to reduce the burden of cardiovascular deaths in both countries.
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spelling doaj-art-a7f94ec74fd64ae9809627fe222e83cb2025-01-11T10:01:04ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632278-71352024-12-0113125621562510.4103/jfmpc.jfmpc_712_24Prevalence of traditional cardiovascular risk factors in high-risk Kyrgyzstan population as compared to Indians − An Indo-Kyrgyz cardiometabolic studyKamal SharmaShilpi MohanS. A. HossainStuti ShahAshwati KonatKomal ShahShubh MehtaJonsi Jayantkumar TavethiaJeel Narendra SarvaiyaSaumya JoshiKaran ShahDhruv Rakeshkumar PatelShlok PatelBackground: Cardiovascular diseases (CVDs) are one of the most prevalent causes of mortality worldwide, especially significant in low- and middle-income countries. Kyrgyzstan and India represent such nations that face a huge burden of CVD-related deaths globally. Understanding the prevalence of traditional cardiovascular risk factors (CVRFs) in these populations is critical for effective prevention and management strategies. Methods: This is a multicentric, observational study where we compared the prevalence of CVRFs in high-risk populations from Kyrgyzstan and India. Data was collected from established ASCVD patients attending cardio-metabolic clinics at tertiary care centers between December 2021 and December 2023. Demographic characteristics and CVRFs, which encompassed diabetes, hypertension, lipid profile parameters, tobacco consumption, etc., were assessed. Statistical analysis was performed to identify significant differences between the cohorts. Results: A total of 1552 individuals (772 from Kyrgyzstan, 750 from India) were studied. The Kyrgyzstan cohort had a significantly higher mean age and a greater proportion of females compared to the Indian cohort. The prevalence of tobacco consumption, hypertension, and diabetes was significantly higher in Kyrgyzstan than in India. Lipid profile analysis revealed greater level of LDL, HDL, and total cholesterol in the Kyrgyzstan cohort. Conversely, triglyceride levels were lower in Kyrgyz individuals. The Kyrgyzstan cohort also demonstrated better left ventricular systolic function compared to the Indian cohort. Discussion: Our study highlights significant differences in the prevalence of traditional CVRFs between high-risk populations in Kyrgyzstan and India. Higher rates of tobacco consumption, hypertension, and diabetes in Kyrgyzstan signify the immediate need for targeted interventions to address these modifiable risk factors. Targeted public health programs focusing on these lifestyle modifications and efficacious management of CVRFs are crucial to reduce the burden of cardiovascular deaths in both countries.https://journals.lww.com/10.4103/jfmpc.jfmpc_712_24atherosclerotic cardiovascular diseasecardiovascular diseasescardiovascular risk factorsindiakyrgyzstan
spellingShingle Kamal Sharma
Shilpi Mohan
S. A. Hossain
Stuti Shah
Ashwati Konat
Komal Shah
Shubh Mehta
Jonsi Jayantkumar Tavethia
Jeel Narendra Sarvaiya
Saumya Joshi
Karan Shah
Dhruv Rakeshkumar Patel
Shlok Patel
Prevalence of traditional cardiovascular risk factors in high-risk Kyrgyzstan population as compared to Indians − An Indo-Kyrgyz cardiometabolic study
Journal of Family Medicine and Primary Care
atherosclerotic cardiovascular disease
cardiovascular diseases
cardiovascular risk factors
india
kyrgyzstan
title Prevalence of traditional cardiovascular risk factors in high-risk Kyrgyzstan population as compared to Indians − An Indo-Kyrgyz cardiometabolic study
title_full Prevalence of traditional cardiovascular risk factors in high-risk Kyrgyzstan population as compared to Indians − An Indo-Kyrgyz cardiometabolic study
title_fullStr Prevalence of traditional cardiovascular risk factors in high-risk Kyrgyzstan population as compared to Indians − An Indo-Kyrgyz cardiometabolic study
title_full_unstemmed Prevalence of traditional cardiovascular risk factors in high-risk Kyrgyzstan population as compared to Indians − An Indo-Kyrgyz cardiometabolic study
title_short Prevalence of traditional cardiovascular risk factors in high-risk Kyrgyzstan population as compared to Indians − An Indo-Kyrgyz cardiometabolic study
title_sort prevalence of traditional cardiovascular risk factors in high risk kyrgyzstan population as compared to indians an indo kyrgyz cardiometabolic study
topic atherosclerotic cardiovascular disease
cardiovascular diseases
cardiovascular risk factors
india
kyrgyzstan
url https://journals.lww.com/10.4103/jfmpc.jfmpc_712_24
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